Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose his/her feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene ...
Nasrollah Saleh-gohari +1 more
doaj +2 more sources
A Pain in the Brain: How PACAP CeA Infusion Alters Mechanical and Thermal Sensitivity [PDF]
Pain is a universal experience, yet the treatment of pain continues to challenge the medical community. The first step toward treating pain is understanding the underlying neurological mechanisms that lead to the perception of pain.
Huessy, Julia Grace
core +1 more source
Consciously feeling the pain of others reflects atypical functional connectivity between the pain matrix and frontal-parietal regions [PDF]
Around a quarter of the population report ‘mirror pain’ experiences in which bodily sensations of pain are elicited in response to viewing another person in pain.
Banissy, Michael J +3 more
core +1 more source
Congenital Insensitivity to Pain and Anhydrosis: A Report of Two Cases
We report on 2 patients with congenital insensitivity to pain and anhydrosis. The first one was a 7-month-old boy who presented with non-traumatic, haematogenous septic dislocation of the right elbow with physeal separation of the distal humerus.
Maharajan Karthikeyan +3 more
doaj +1 more source
Neglected painless wounds in a child with congenital insensitivity to pain
A 13-year-old boy was brought by his mother for neglected toes wounds. There was a history of self-mutilation from first years of life with absence of normal reaction to painful stimuli. He had scars from injuries and he had self-mutilation of the distal
Ali Akhaddar, Mohamed Malih
doaj +1 more source
Phenomenal knowledge why: the explanatory knowledge argument against physicalism [PDF]
Phenomenal knowledge is knowledge of what it is like to be in conscious states, such as seeing red or being in pain. According to the knowledge argument (Jackson 1982, 1986), phenomenal knowledge is knowledge that, i.e., knowledge of phenomenal facts ...
Mørch, Hedda Hassel
core
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels [PDF]
Voltage-gated ion channels (VGICs) are membrane proteins that switch from a closed to open state in response to changes in membrane potential, thus enabling ion fluxes across the cell membranes.
Alessandro eMedoro +7 more
core +2 more sources
NGF – the TrkA to successful pain treatment [PDF]
Chronic pain arising from various pathological conditions such as osteoarthritis, low back or spinal injuries, cancer, and urological chronic pelvic pain syndromes presents significant challenges in diagnosis and treatment.
Kumar, Vinayak, Mahal, Brandon
core +1 more source
SCN9A channelopathy associated autosomal recessive Congenital Indifference to Pain : a case report
Background: Congenital Indifference to Pain (CIP) is a rare condition that inhibits the ability of patients to perceive physical pain but otherwise keeps normal sensory modalities.
Cauwels, Rita +3 more
core +1 more source
Thermal quantitative sensory testing in healthy Dutch children and adolescents standardized test paradigm and Dutch reference values [PDF]
Background: Quantitative sensory testing (QST) is often used to measure children's and adults' detection- and pain thresholds in a quantitative manner.
Bosch, G.E. (Gerbrich) van den +3 more
core +3 more sources

