Results 101 to 110 of about 8,099 (218)

Preserved emotional awareness of pain in a patient with extensive bilateral damage to the insula, anterior cingulate, and amygdala [PDF]

open access: yes, 2016
Functional neuroimaging investigations of pain have discovered a reliable pattern of activation within limbic regions of a putative "pain matrix" that has been theorized to reflect the affective dimension of pain.
A Biemond   +72 more
core   +1 more source

A disease mutation reveals a role for Nav1.9 in acute itch [PDF]

open access: yes, 2018
Itch (pruritis) and pain represent two distinct sensory modalities; yet both have evolved to alert us to potentially harmful external stimuli. Compared with pain, our understanding of itch is still nascent.
Bosmans, Frank   +5 more
core   +1 more source

Update Review and Clinical Presentation in Congenital Insensitivity to Pain and Anhidrosis

open access: yesCase Reports in Pediatrics, 2015
Introduction. Congenital insensitivity to pain and anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV is an extremely rare syndrome.
L. M. Pérez-López   +4 more
doaj   +1 more source

Spectrum of neuropathic skeletal injuries in children: a pictorial essay

open access: yesInsights into Imaging
Neuropathic skeletal injuries in children are common manifestations of conditions associated with sensory impairment. The underlying aetiologies may be rare entities such as congenital insensitivity to pain or more prevalent disorders such as spinal ...
Maria Chiara Bonanno   +7 more
doaj   +1 more source

Congenital Insensitivity to Pain: A Case Report and Review of the Literature

open access: yesCase Reports in Neurological Medicine, 2014
Congenital insensitivity to pain (CIP) is a rare autosomal recessive genetic disease caused by mutations in the SCN9A gene. We report a patient with the clinical features consistent with CIP in whom we detected a novel homozygous G2755T mutation in exon ...
Leema Reddy Peddareddygari   +2 more
doaj   +1 more source

Congenital Insensitivity to Pain [PDF]

open access: yesJournal of the Royal Society of Medicine, 1991
openaire   +2 more sources

Deciphering the Structural and Functional Effects of the R1150W Non-Synonymous Variant in SCN9A Linked to Altered Pain Perception

open access: yesNeuroSci
The SCN9A gene, a critical regulator of pain perception, encodes the voltage-gated sodium channel Nav1.7, a key mediator of pain signal transmission.
Faisal A. Al-Allaf   +2 more
doaj   +1 more source

Main therapeutic and rehabilitation actions in patients with congenital insensitivity to pain

open access: yesUniversidad Médica Pinareña, 2020
Introduction: congenital insensitivity to pain is a hereditary whose main characteristic is absolute analgesia to pain. Objective: to describe the main existing therapeutic actions for patients with congenital insensitivity to pain in its diverse ...
Noel Jesús Niebla-Gómez   +2 more
doaj  

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