Results 101 to 110 of about 23,188 (240)

Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent

Experimental Physiology, Volume 111, Issue 1, Page 54-68, 1 January 2026.
Abstract Oestradiol (17β‐E2) is reported to prolong the cardiac action potential duration and QT interval, in part by affecting cardiac ion channels. Previous studies found inhibiting 17β‐E2 effects on the repolarizating cardiac KV7.1/KCNE1 channel, or its native current, in heterologous expression systems or tissue from animal species.
Veronika A. Linhart, Lucas Dauga, Sara I. Liin   +2 more
wiley   +1 more source

[Congenital long QT syndrome].

Herz, 2007
The long QT syndrome is characterized by prolongation of the heart rate-corrected QT interval on the electrocardiogram and by the occurrence of life-threatening ventricular tachyarrhythmias of the torsade de pointes type. In most cases, the disorder becomes clinically manifest during childhood.
Najeeb, Ahmed, Kamran, Riaz, Ripudeep, Rai, Mohammed, Osman, Abdul, Wase   +4 more
openaire   +3 more sources

Implantable cardioverter defibrillator therapy in pediatric and congenital heart disease patients: a single tertiary center experience in Korea [PDF]

, 2013
PurposeThe use of implantable cardioverter defibrillators (ICDs) to prevent sudden cardiac death is increasing in children and adolescents. This study investigated the use of ICDs in children with congenital heart disease.MethodsThis retrospective study ...
Berul, Bo Kyung Jin, Bo Sang Kwon, Bonney, Botsch, Celiker, Choi, Chung Il Noh, Cross, Eicken, Eun Jung Bae, Eun Young Choi, Fananapazir, Gi Beom Kim, Heersche, Hobbs, Horner, Hsia, Ji Seok Bang, Jung Yun Choi, Kral, Kriebel, Kwon, Lobodzinski, Panfilov, Shah, Silka, Tester, Von Bergen, Woong Han Kim, Wren   +30 more
core   +1 more source

Hope in Miniature: The First Case of Implantation of a “Tiny Pacemaker” in Italy as a Successful Treatment for Congenital Atrioventricular Block in a Low Birth Weight Child

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Congenital complete atrioventricular block (CAVB) is a rare cardiac condition occurring in approximately one in 15,000 to one in 22,000 live births. Maternal autoimmune diseases, with anti‐ssA (Ro) and anti‐ssB (La) antibodies implicated in 56%–90% of cases, are primary causes.
Ferrari Paola, Limonta Raul, Malanchini Giovanni, Patanè Luisa, De Filippo Paolo, Karuna Sharma   +5 more
wiley   +1 more source

Jervell and Lange-Nielson Syndrome masquerading as intractable epilepsy

Annals of Indian Academy of Neurology, 2012
The long QT syndrome (LQTS) is a cause of syncope and sudden death. Jervell and Lange-Nielson syndrome (JLNS) is an uncommon form of LQTS, having autosomal recessive transmission, and is associated with congenital deafness.
Jagdish P Goyal, Alka Sethi, V B Shah
doaj   +1 more source

Sodium leak through K2P potassium channels and cardiac arrhythmia, an emerging theme. [PDF]

, 2017
In this issue of EMBO Molecular Medicine, Decher et al (2017) identify a point mutation in the K2P2 (TREK‐1) potassium (K+) channel that changes function in just those ways expected to predispose to right ventricular outflow tract (RVOT) ventricular
Goldstein, Steve An
core   +2 more sources

Postpump Chorea After Pediatric Cardiac Surgery: Exploring Causes and Treatment

Journal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Introduction Postpump chorea is a rare but potentially disabling movement disorder that arises days to weeks after cardiopulmonary bypass, most often following deep hypothermic circulatory arrest in pediatric patients undergoing repair of complex congenital heart defects. Clinically, postpump chorea presents as involuntary, nonrhythmic, choreiform, and
Jad Abdul Khalek, Karim Kanbar, Fadi Bitar, Mariam Arabi, Randy Stevens   +4 more
wiley   +1 more source

Masquerade of a Silent Killer

Oman Medical Journal, 2011
Congenital long QT syndrome (LQTS), referred to as a ticking time-bomb is a cause of sudden death in young infants, children and adults.1 Its prevalence is estimated to be 1 in 2500 to 1 in 10,000 individuals internationally, with no racial predilection ...
Padmini Venkataramani, Muthuswamy Ramaswamy   +1 more
doaj  

T-wave alternans in long QT syndrome

Annals of Pediatric Cardiology, 2018
Long QT syndrome (LQTS) is a congenital disorder characterized by prolongation of QT interval in the electrocardiogram (ECG) and a propensity to develop ventricular arrhythmias, which may lead to syncope, cardiac arrest or sudden death. T-wave alternans (
Siddharth Narayan Gadage
doaj   +1 more source

The U wave in atrial fibrillation [PDF]

, 2015
The U wave in ECGs of patients is difficult to observe because it is hidden under the atrial fibrillatory wave. Measurement and characteristics of the U wave in atrial fibrillation have not previously been described. Beat averaging was used to reveal the
Bourke, John P, Langley, Philip, Murray, Alan   +2 more
core   +1 more source