The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review [PDF]
, 2022 D. Tardo +4 more
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Ion channels: structural basis for function and disease. [PDF]
, 1996 Ion channels are ubiquitous proteins that mediate nervous and muscular function, rapid transmembrane signaling events, and ionic and fluid balance. The cloning of genes encoding ion channels has led to major strides in understanding the mechanistic basis
Goldstein, SA
core +1 more source
Genotype-Phenotype Relationships in Long QT Syndrome : Role of Mental Stress, Adrenergic Activity and a Common KCNH2 Polymorphism [PDF]
, 2006 Long QT syndrome is a congenital or acquired arrhythmic disorder which manifests as a prolonged QT-interval on the electrocardiogram and as a tendency to develop ventricular arrhythmias which can lead to sudden death.
Paavonen, Kristian
core
Prevalencia de patrones electrocardiográficos asociados a muerte súbita en la población española de 40 años o más. Resultados del estudio OFRECE [PDF]
, 2017 [Abstract] Introduction and objectives. Some electrocardiographic patterns are associated with an increased risk of sudden cardiac death due to ventricular arrhythmias. There is no information on the prevalence of these patterns in the general population
Alonso Martín, Joaquín Jesús +11 more
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A Congenital Deadly Association: Dilated Cardiomyopathy and Long QT Syndrome
Journal of Cardiac Arrhythmias, 2020 Long QT syndrome is one of the most feared entities in hospitalized patients due to the potential risk for ventricular tachycardia and sudden death. Association between channelopathies and congenital cardiomyopathy is a new entity that has been studied ...
Neiberg de Alcantara Lima +3 more
doaj +4 more sources
Scoping Review of Experience of People living with Inherited Cardiac Conditions and Congenital Heart Disease. The experience of individuals with inherited cardiac conditions and congenital heart disease and their families throughout the life course: impact, difficulties and resilience [PDF]
, 2015 This was a scoping review of the experiences of people with inherited cardiac conditions and congenital heart disease and their families. The Irish Heart Foundation is trying to investigate the issues which these individuals and their families might face
Burns, Annette +2 more
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A MATLAB algorithm to automatically estimate the QT interval and other ECG parameters and validation using a machine learning approach in congenital long-QT syndrome [PDF]
, 2023 Elinor Tzvi +3 more
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MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]
, 2014 Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Anting L. Carlsen +59 more
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The congenital long QT syndromes in childhood
Journal of the American College of Cardiology, 1990 Twenty-three children and young persons with a congenital long QT syndrome were identified; the median age at the time of referral was 10 years (range 4 days to 19 years) and 14 patients (61%) had a family history of the syndrome. Among the 19 patients with symptoms, the initial symptom was syncope in 13 (69%), aborted sudden death in 5 (26%) and near ...
Weintraub, Robert G. +2 more
openaire +2 more sources
Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]
, 2014 Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J +2 more
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