Results 41 to 50 of about 7,883,789 (150)

Safety and Utility of Smartphone‐Based Heart Monitors in Pediatric Patients With Cardiovascular Implantable Electronic Devices

Journal of Cardiovascular Electrophysiology, EarlyView.
Smartphone heart monitors in pediatric CIEDs: A pilot study. Smartphone heart monitors did not induce EMI in children with CIEDs, enabling reliable heart rate measurement and accurate identification of ventricular non‐captures. ABSTRACT Background Portable heart monitors enable on‐demand electrocardiogram (ECG) recordings and enhance symptom‐rhythm ...
Chun‐Lok Ho, Sit‐Yee Kwok, Sabrina S. L. Tsao, Yiu‐Fai Cheung   +3 more
wiley   +1 more source

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome—Results of the German Multicenter Study COGIA

Journal of Cardiovascular Electrophysiology, EarlyView.
The study examines 76 patients of the German multicenter study COGIA with suspected BrS in 12 centers in Germany. Thirty‐nine patients met the current ESC diagnostic criteria, 34 of whom met the Shanghai Score criteria. Four major arrhythmic events (ACA, SCD, appropriate ICD shock) occurred in the cohort (5.3%), all in the group of patients fulfilling ...
Lea Lippert, Tobias Burkard, Franziska Markel, Volker Debus, Fridrike Stute, Anna Kamphues, Robert Dalla Pozza, Stefan Rupp, Maria B. Gonzalez y Gonzalez, Claudia Junge, Majed Kanaan, Kirstin Hoff, Anja Hanser, Sven Dittmann, Dominik Sebastian Westphal, Isabel Diebold, Sebastian Clauß, Stefanie Kessner, Marc‐Phillip Hitz, Kolja Becker, Stefan Kääb, Peter Ewert, Michael Hofbeck, Wolfgang Wällisch, Sven Dittrich, Anselm Uebing, Stephan Neumann, Jan‐Hendrik Nürnberg, Joachim Hebe, Rainer Kozlik‐Feldmann, Philipp Beerbaum, Gunter Kerst, Eric Schulze‐Bahr, Roman Gebauer, Gabriele Hessling, Cordula Maria Wolf   +35 more
wiley   +1 more source

Late-onset severe long QT syndrome.

, 2017
We report a case of torsades de pointes arrhythmia as the first manifestation of congenital Long QT syndrome in a 77-year-old man with family history of sudden unexplained death.
Schaller, André, Bartholdi, Deborah, André Schaller, Deborah Bartholdi, Medeiros Domingo, Argelia, Argelia Medeiros-Domingo, Babken Asatryan, Asatryan, Babken, Bartholdi D, Medeiros-Domingo A, Asatryan B, Schaller A   +11 more
core   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

A rare association of long QT syndrome, syndactyly and atrial septal defect (timothy syndrome) – Case report and literature review

IHJ Cardiovascular Case Reports, 2017
Timothy syndrome (TS) is a rare genetic disorder characterized by an abnormally prolonged cardiac “repolarization” time (long QT interval). This predisposes individuals to arrhythmias, cardiac arrest and sudden death.
Bhupendra K. Sihag, Vikas Agrawal
doaj   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

[Congenital long QT syndrome].

, 1998
International audienceSEVERAL FORMS: Congenital long QT syndrome is a clinically (with and without deafness) and genetically (recessive or dominant autosomal inheritance) heterogeneous entity characterized by a long QT interval on the ECG associated with
Neyroud, N, Guicheney, P, Coumel, P, Casasoprana, A, Denjoy, I, Lupoglazoff, J   +5 more
core   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, Volume 46, Issue 6, Page 1939-1957, November 2026.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Anesthetic Management of a Patient with Congenital Long QT Syndrome [PDF]

, 2004
Long QT syndrome is characterized by syncope and fatal ventricular arrhythmia or fibrillation at an young age. A 25-year-old female patient with congenital Long QU syndrome (Jervell and Lange-Nielsen syndrome) was scheduled for cochlea implantation due ...
구본녀, 강원철, 길혜금, 박윤곤   +3 more
core  

Drug-Induced QT Prolongation as a Result of an Escitalopram Overdose in a Patient with Previously Undiagnosed Congenital Long QT Syndrome

Case Reports in Medicine, 2014
We present a case of drug-induced QT prolongation caused by an escitalopram overdose in a patient with previously undiagnosed congenital LQTS. A 15-year-old Caucasian female presented following a suicide attempt via an escitalopram overdose.
Paul Singh, J. Martin Maldonado-Duran
doaj   +1 more source