Results 61 to 70 of about 7,883,789 (150)

Myelination and Remyelination in Peripheral Nerve Injury: Mechanisms, Regulation, and Therapeutic Perspectives

MedComm, Volume 7, Issue 10, October 2026.
Peripheral nerve injury triggers axonal degeneration, myelin breakdown, and Schwann cell reprogramming. Remyelination requires reactivation of the SOX10–OCT6–KROX20/EGR2 transcriptional hierarchy, axonal NRG1–ErbB2/3 signaling, metabolic support, and coordinated immune regulation.
Li‐Xin Huang, Tao Sun, Yi‐Bo Zhao, Zhi‐Min Wu, Jun Sun, Ming‐Yang Li, Qing‐Yi Huo, Yun‐Mou Ou, Qing‐Tian Liang, Cong Ling, Bao‐Yu Zhang, Chuan Chen, Ying Guo, Hui Wang   +13 more
wiley   +1 more source

Refractory Ventricular Tachycardia in a Long QT Syndrome Child Successfully Controlled by Left Cardiac Sympathetic Denervation

Pediatrics and Neonatology, 2012
Long QT syndrome is a congenital disorder accompanied by a high incidence of sudden cardiac death. β-adrenergic blockade is the therapy of choice, and it is successful in 75–80% of patients.
Jih-Chin Chang, Chung-Ping Hsu, Betau Hwang, Pi-Chang Lee, Chi-Ren Tsai, Ming-Chih Lin, Sheng-Ling Jan, Yun-Ching Fu   +7 more
doaj   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Methylphenidate and Long‐Term Risk of Cardiovascular Diseases: A Nationwide Cohort Study

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Cardiovascular safety of methylphenidate remains a matter of debate. Methods To evaluate the long‐term cardiovascular risk associated with methylphenidate use, a cohort study was conducted using the French National Health Data System.
Christelle Berthod, Thomas Loppinet, Marietou Ndiaye, Inesse Boussaha, Matthias Jacquet‐Lagreze, Behrouz Kassaï‐Koupai   +5 more
wiley   +1 more source

Modulating effects of age and gender on the clinical course of long QT syndrome by genotype

, 2003
Modulating effects of age and gender on the clinical course of long QT syndrome by ...
Vincent GM, Zhang L, Lehmann MH, Timothy K, International Long QT Syndrome Registry, PRIORI, SILVIA GIULIANA, Hall WJ, SCHWARTZ, PETER, Moss AJ, Peterson DR, Benhorin J, Locati EH, Robinson JL, Zareba W, Towbin JA, Andrews ML, Medina A, Napolitano C   +17 more
core  

Prenatal exome sequencing of fetuses with central nervous system anomalies based on prenatal ultrasound and magnetic resonance imaging diagnosis: A retrospective cohort study with a systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1950-1964, October 2026.
Prenatal exome sequencing significantly improves diagnostic yield over chromosomal microarray analysis for fetal CNS abnormalities, with a diagnostic yield of 16% in our cohort and 27% in the meta‐analysis. Diagnostic yields vary across different phenotypes. Abstract Introduction Fetal central nervous system (CNS) abnormalities have diverse etiologies,
Jia Yao, Yan Wang, Gang Li, Zhitao Zhang, Yuan Lv, Lizhu Chen   +5 more
wiley   +1 more source

The long QT syndrome [PDF]

, 2010
peer reviewedThe congenital long QT syndrome (LQTS) is a hereditary cardiac disease characterized by a prolongation of the QT interval > 440 ms at rest ECG associated with a high risk of ventricular arrhythmias (torsade de pointe).
D'Orio, Vincenzo, MELON, Pierre, LANCELLOTTI, Patrizio, PIERARD, Luc, GARWEG, Christophe   +4 more
core   +1 more source

The importance of the epinephrine provocation test for the hidden type-1 congenital long QT syndrome

Türk Kardiyoloji Derneği Arşivi, 2020
Congenital long QT syndrome (LQTS) is a genetic channelopathy associated with a high incidence of sudden cardiac death in children and young adults. QT interval prolongation is typically the primary finding on the electrocardiography (ECG) recordings ...
Adem Atici, Ramazan Asoğlu, Hasan Ali Barman, Irfan Sahin   +3 more
doaj   +1 more source

QT Interval Evaluation in Right Ventricular Pacing: Validation of a Novel Formula

Pacing and Clinical Electrophysiology, Volume 49, Issue 10, Page 1455-1463, October 2026.
ABSTRACT Background QT interval measurement in the presence of right ventricular pacing (RVP) represents a clinical challenge. We therefore aimed to derive and validate a formula for QT estimation during RVP in a large cohort of pacemaker patients. Methods and Results We prospectively enrolled 100 patients in a derivation cohort and 487 in a validation
Amr Abdin, Alhasan Almasri, Ibrahim Antoun, Charles Gieres, Christian Werner, Yvonne Bewarder, Christian Ukena, Igor Schwantke, Michael Böhm, Saarraaken Kulenthiran   +9 more
wiley   +1 more source

Two:One atrioventricular block in infants with congenital long QT syndrome

, 1987
Congenital prolongation of the QT interval is a rare but life-threatening disorder of the cardiac conduction system.1-5 The disorder usually presents as syncope or sudden death due to complex polymorphic ventricular tachycardia (torsade de pointes) or ...
Dick, Macdonald II, Scott, William A.
core   +1 more source