PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin +11 more
wiley +1 more source
Posiciones sustancialmente preponderantes y costas procesales
El presente artículo propone un mecanismo legal de aplicación excepcional (llamado "declaración de posición sustancialmente preponderante gracias al cual los tribunales colombianos podrían resolver en forma sumaria sobre la responsabilidad ...
Fernando García-Forero
doaj
A Contention-Based Hop-By-Hop Bidirectional Congestion Control Algorithm for Ad-Hoc Networks
Existing hop-by-hop congestion control algorithms are mainly divided into two categories: those improving the sending rate and those suppressing the receiving rate. However, these congestion control algorithms have problems with validity and limitations.
Jiashuai Wang +3 more
doaj +1 more source
A General and Efficient Framework for the Rapid Design of Miniaturized, Wideband, and High‐Bit RIS
A general and efficient framework is proposed for the rapid design of high‐performance reconfigurable intelligent surfaces (RISs). This framework integrates advanced antenna design techniques and incorporates various load types, quantities, and values to achieve the design of high‐performance RISs.
Jun Wei Zhang +14 more
wiley +1 more source
Aglomeración Económica y Congestión Vial: los Perjuicios por Racionamiento del Tráfico Vehicular [PDF]
La creciente urbanización latinoamericana de las últimas décadas ha inducido mayor demanda de vehículos y congestión de tráfico. Pretendiendo aliviar los costos de la congestión se han adoptado medidas polémicas que restringen la circulación del 20% o el
Carlos Alberto Medina +1 more
core
El impacto espacial de las economías de aglomeración y su efecto sobre la estructura urbana.El caso de la industria en Barcelona, 1986-1996 [PDF]
Este trabajo trata sobre el papel de la accesibilidad espacial a las economías de aglomeración en el cambio de la estructura espacial del empleo industrial para el caso de la Región Metropolitana de Barcelona (RMB).
García López, Miquel-Àngel +2 more
core
Empirical study on the use of public transport in the Community of Madrid as a key factor in sustainable mobility [PDF]
The level of public transport use in the area of large cities is representative of the degree of sustainable mobility behavior. This article, based on a population survey of mobility in the Community of Madrid are and the approach of a set of hypotheses ...
Jiménez Barandalla, Iciar Carmen +2 more
core +2 more sources
Research Progress and Applications of Non‐Carrier‐Injection Electroluminescence
Non‐carrier‐injection electroluminescence (NCI‐EL) uses AC fields and displacement currents to trigger light from internal charge reservoirs, enabling minimalist emitters with remotely coupled terminals. This review maps shared mechanisms across organics, GaN, quantum dots, and TMDCs, compares planar, interdigital, single‐terminal, and coaxial designs,
Wei Huang +6 more
wiley +1 more source
We identify two decisive levers for SAM interfaces: molecular design (carboxylic acid‐based, phosphonic acid, other anchoring chemistries, and polymeric SAMs) and mixing routes (co‐assembly, in situ assembly, pre‐ and post‐treatment). Coordinated tuning of headgroups and assembly pathways optimises energy alignment and film formation, suppresses ...
Jiaxu Zhang, Bochun Kang, Feng Yan
wiley +1 more source
Tratamiento de la congestión en el síndrome cardiorrenal tipo 1
El síndrome cardiorrenal resulta de una relación estrecha entre corazón y riñón. Se han definido cinco fenotipos de esta compleja interacción. El tipo 1 se caracteriza por insuficiencia cardiaca aguda que genera una lesión renal aguda; usualmente, se ...
Orlando D. Navarro-Ulloa +4 more
doaj +1 more source

