Results 81 to 90 of about 654,160 (322)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

Simulation-Based Optimization of Truck Appointment Systems in Container Terminals: A Dual Transactions Approach with Improved Congestion Factor Representation

open access: yesLogistics
Background: Container terminals (CTs) have constantly administered truck appointment systems (TASs) to effectively accomplish the planning and scheduling of drayage operations.
Davies K. Bett   +3 more
doaj   +1 more source

Simulation comparison of RED and REM [PDF]

open access: yes, 2000
We propose earlier an optimization based low control for the Internet called Random Exponential Marking (REM). REM consists of a link algorithm, that probabilistically marks packets inside the network, and a source algorithm, that adapts source rate to ...
Athuraliya, Sanjeewa, Low, Steven H.
core   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Soluble CD146 in Heart Failure: Pathophysiological Role and Diagnostic Potential

open access: yesBiomedicines
Heart failure (HF) remains a major global health challenge, driven by multifactorial pathophysiological processes, such as systemic congestion, endothelial dysfunction, and inflammation.
Daniela Mocan   +8 more
doaj   +1 more source

An Efficient Staged Evacuation Planning Algorithm Applied to Multi-Exit Buildings

open access: yesISPRS International Journal of Geo-Information, 2020
When the occupant density of buildings is large enough, evacuees are prone to congestion during emergency evacuation, which leads to the extension of the overall escape time.
Litao Han   +5 more
doaj   +1 more source

Congestion: Relation between traditional DEA congestion and two-stage processes congestion

open access: yesRAIRO - Operations Research
Congestion is a kind of inefficiency because it causes the decision-making units (DMUs) to be inefficient and reduces their output. Identifying inefficient DMUs and determining the cause of their inefficiencies has been one of the most important reasons for referring to the internal structure of DMUs and analyzing the effect of intermediate products on
Seyed Rahim Moosavi   +1 more
openaire   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

open access: yesAdvanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye   +5 more
wiley   +1 more source

Printemps arabe : de l’événement à la formule discursive

open access: yesMultilinguales, 2018
The expression of "Arab Spring" designating the movements that broke out in 2011 in Tunisia and then in other Arab countries, has occupied a considerable place in political, media and public speeches.
Nadjia Nehari-Roubai, Farid Benramdane
doaj   +1 more source

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