Results 171 to 180 of about 9,088,855 (308)

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

Perioperative Management of Decompensated Peripartum Cardiomyopathy With Severe Left Ventricular Dysfunction: A Case Report. [PDF]

Cureus
Ramkeesoon R, Sang AC, Singh K, Ramdin C.   +3 more
europepmc   +1 more source

Efficiency and Perceptions in Public CSR: An Integrated Efficiency–Perception Analysis of Spanish Defence Delegations

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Public organisations often experience a discrepancy between improvements in technical efficiency and stakeholders' perceptions of integrity and performance. This study analyses the mechanisms that may underlie this efficiency–perception discrepancy in Spanish Defence Delegations during 2020–2023.
José Solana‐Ibáñez, Manuel Caravaca‐Garratón   +1 more
wiley   +1 more source

Universal scaling laws in freeway traffic. [PDF]

PNAS Nexus
Lee G, Jha A, Wiesenfeld K, Laval J.
europepmc   +1 more source

Impact of Drone Versus Car Transport on Anti‐Doping Sample Integrity Over Short Distances: A Proof‐Of‐Concept Study

Drug Testing and Analysis, EarlyView.
This proof‐of‐concept study evaluated the impact of short‐distance drone transport on anti‐doping sample integrity compared with traditional car transport. Targeted assays and untargeted metabolomics revealed equivalent biological profiles between methods, confirming that drone delivery preserves sample integrity for the athlete biological passport ...
I. Al‐Mohannadi, M. Y. Al‐Jaber, M. Al‐Nesf, W. Samsam, Abdulaziz Farooq, N. M. Thomas, M. Stuart, N. Robinson, G. Zangenfeind, D. Rovira, N. Mohamed‐Ali, A. Beotra, V. Mohamed‐Ali, M. Al‐Maadheed   +13 more
wiley   +1 more source

Unveiling spatial heterogeneity in urban underground space development patterns and mechanisms for differentiated planning: A points of interest‐based study of Shanghai

Deep Underground Science and Engineering, EarlyView.
This study investigated the spatial patterns and development mechanisms of urban underground space (UUS) in Shanghai using underground points of interest data. It revealed distinct development mechanisms between the main city and suburbs, highlighting the need for differentiated UUS planning and policies to optimize underground space resources ...
Chenxiao Ma, Fangle Peng, Yongkang Qiao, Yunhao Dong   +3 more
wiley   +1 more source

Carbon emission assessment of tunnel infrastructures: From construction to operation

Deep Underground Science and Engineering, EarlyView.
This study develops a lifecycle carbon accounting framework for tunnel infrastructures, covering design, construction, operation, maintenance, and dismantling. Applied to a subsea tunnel case, the framework reveals the carbon emission distribution among four typical tunnel types and highlights potential carbon offset methods for low‐carbon tunnel ...
Luyuan Long, Wout Broere, Xuehui Zhang, Tian Xia, Richard de Nijs   +4 more
wiley   +1 more source

From prognostication to implementation: the next frontier for ultrasound-guided assessment of decongestion. [PDF]

Eur Heart J Imaging Methods Pract
Koratala A, Kazory A.
europepmc   +1 more source

Molecular Modification Strategies for CO2 Electroreduction to C2+ Products: Classifications, Mechanisms, Advances, and Perspectives

EcoEnergy, EarlyView.
This review comprehensively outlines molecular modification strategies for steering CO2 electroreduction toward C2+ products, including the classification of diverse molecular structures, elucidation of their roles in microenvironment regulation, dissection of C–C coupling pathway engineering, and forward‐looking perspectives on machine learning and ...
Lingling Peng, Hanwen Liu, Tianyou Peng
wiley   +1 more source

Operative management of penile strangulation caused by a rigid metallic ring: a case report. [PDF]

J Surg Case Rep
Asim N, Abdalla M, Martin S.
europepmc   +1 more source