Results 31 to 40 of about 59,062 (321)
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Electromagnetic conic sections [PDF]
Certain orthogonal coordinate systems naturally correspond to basis vectors which are both curl-free and divergence-free, and hence solve Maxwell’s equations. After first comparing several different traditional approaches to computing div, grad, and curl in curvilinear coordinates, we present a new approach, based on these “electromagnetic” basis ...
Tevian Dray, Corinne A. Manogue
openaire +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
FERTILIZER METERING MECHANISM WITH HELICAL CONIC CYLINDRICAL THREAD FOR FAMILY AGRICULTURE [PDF]
Small rural farms are important for Brazilian agribusiness, but equipment suitable for distributing fertilizers on these properties is scarce. We studied a new fertilizer metering mechanism for use on the family farm.
Cezario B. Galvão +3 more
doaj +1 more source
Micro Aspheric Convex Lenses Fabricated by Precise Scraping
An easy, fast, inexpensive, and simple method utilizing a microshaper with a very small knife nose is used to fabricate microconvex aspherical lenses. The microshaper is mounted on a computer numerical control (CNC) machine.
Meng-Ju Lin
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Analysis of Students’ Mathematical Representation Ability in Working on Conical Section Problems
This study aims to analyze students’ representational ability in working on conic section problems. This study is included in case study research using a qualitative approach. The subjects of this study were students of Widya Dharma University.
Muhammad Ridlo Yuwono +2 more
doaj +1 more source
CSD: Discriminance with Conic Section for Improving Reverse k Nearest Neighbors Queries
The reverse $k$ nearest neighbor (R$k$NN) query finds all points that have the query point as one of their $k$ nearest neighbors ($k$NN), where the $k$NN query finds the $k$ closest points to its query point. Based on the characteristics of conic section,
Bai, Mingyuan +5 more
core
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source

