Results 181 to 190 of about 1,098,878 (302)

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan   +9 more
wiley   +1 more source

Protocol for preparation of mouse synovium for flow cytometry and RNA-seq. [PDF]

STAR Protoc
Montgomery AB, Cuda CM, Dominguez S, Makinde H, Misharin AV, Wang Y, Yunda de Miguel A, Winter DR, Perlman H.   +8 more
europepmc   +1 more source

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

Annals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai, Joanne Wuu, Magdalena Koziczak‐Holbro, Andrea Malaspina, Volkan Granit, Jessica P. Hernandez, Anne Cooley, Ruchika Sachdev, Lili Yu, Michael Bidinosti, Ludivine Flotte, Mark Nash, Lori L. Jennings, James D. Berry, Lucie I. Bruijn, Sophie Brachat, Michael Benatar   +16 more
wiley   +1 more source

Acid‐ and Nucleophile‐Gated Photoisomerization of Phosphaindirubin

Angewandte Chemie, EarlyView.
Triply gated isomerization: In polar solvents, a phosphorus‐containing indirubin photoswitch undergoes visible‐light‐driven Z→E isomerization only when protonated, and reverts thermally via nucleophile‐catalyzed back‐isomerization. This three‐way control by light, acid, and nucleophile enables reversible photoisomerization.
Jacob Jan van der Wal, Jorn D. Steen, Ann‐Kathrin Rückert, Roman Yu. Peshkov, Michiel F. Hilbers, P. Tim Prins, Wybren Jan Buma, Andreas Orthaber, Stefano Crespi   +8 more
wiley   +2 more sources

Thermal decomposition behavior and sustainable recycling of flexible perovskite solar modules. [PDF]

Chem Sci
Shi X, Liu Y, Liu T, Luo S, Wang F, Chen S.   +5 more
europepmc   +1 more source

Non‐Synaptic Function and Localization of Syntaxin‐Binding Protein 1 in a Mouse Model of STXBP1‐Related Epileptic Encephalopathy

Annals of Neurology, EarlyView.
Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang, Rajat Banerjee, Yamei Deng, Sheetal Jahagirdar1, Alexey I. Nesvizhskii, Michael D. Uhler, Jack M. Parent, Yu Wang   +7 more
wiley   +1 more source

Machine learning photodynamics reveal intersystem-crossing-driven ladderdiene ring opening. [PDF]

Chem Sci
Li Z, Fu H, Lopez SA, Li J.
europepmc   +1 more source

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

Annals of Neurology, EarlyView.
Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains a significant challenge.
Yue Qiao, Adrien Ter Schiphorst, Yi Xu, Jean‐Claude Baron, Wenbo Zhao   +4 more
wiley   +1 more source

Spin Hall magnetoresistance and spin Seebeck effect in Pt |CoCr₂O₄ heterostructures. [PDF]

Sci Technol Adv Mater
Aqeel A, Kronseder M, Vlietstra N, Huebl H, Heuver JA, Noheda B, Herrero-Martín J, Pellegrin E, Vasili HB, Mostovoy M, Back C.   +10 more
europepmc   +1 more source

Super-resolution femtosecond electron diffraction reveals electronic and nuclear dynamics at conical intersections. [PDF]

Nat Commun
Jiang H, Zhang J, Wang T, Peng J, Jin C, Zou X, Zhu P, Jiang T, Lan Z, Yong H, He F, Xiang D.   +11 more
europepmc   +1 more source