Results 111 to 120 of about 579 (230)

Paleomagnetism indicates that primary magnetite in zircon records a strong Hadean geodynamo. [PDF]

Proc Natl Acad Sci U S A, 2020
Tarduno JA, Cottrell RD, Bono RK, Oda H, Davis WJ, Fayek M, Erve OV', Nimmo F, Huang W, Thern ER, Fearn S, Mitra G, Smirnov AV, Blackman EG.   +13 more
europepmc   +1 more source

Natural selection according to Darwin: cause or effect? [PDF]

Hist Philos Life Sci, 2022
Bradley B.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

A cross-sectional study of policies from American medical organizations about public communications from physicians in the digital age. [PDF]

Sci Rep
Smith AJ, Hachen S, Oquendo MA, Bhugra D, Ventriglio A, Liebrenz M.   +5 more
europepmc   +1 more source

The trace in the technique: Forensic science and the Connoisseur's gaze. [PDF]

Forensic Sci Int Synerg, 2021
Miranda MD.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Consent and its discontents: the case of UK Biobank. [PDF]

Med Health Care Philos
Barn G.
europepmc   +1 more source

Mapping the International Geopolitical Agenda: Still National Conceptions of the Emerging European Crisi. [PDF]

Front Big Data, 2021
Grasland C, Toureille E, Leconte R, Severo M.   +3 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source