Results 181 to 190 of about 573 (222)

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Repositioning Construct Validity Theory: From Nomological Networks to Pragmatic Theories and Their Evaluation by Explanatory Means. [PDF]

Perspect Psychol Sci
Haig BD.
europepmc   +1 more source

A CRITICAL TEST DATA FOR THE ABC CONJECTURE

openaire   +2 more sources

Book Review : ‘A cheap, safe and natural medicine’: religion, medicine and culture in John Wesley’s

Med Hist, 2009
europepmc   +1 more source

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Apollonius Resartus: A Study in Conjectural Criticism

Classical Philology, 1980
FOR centuries readers of the influential Historia Apollonii Regis Tyri had been misconceiving its style and composition. The reason? In retrospect, simple: the tale had been edited under false premises. It had been edited as if the finished product might possess a single uniformity; as if, in effect, a motley pack of MSS whose line of division is ...
J M Hunt
exaly   +2 more sources

On the double-critical graph conjecture

Discrete Mathematics, Algorithms and Applications, 2022
A connected graph [Formula: see text] is double-critical if the chromatic number of [Formula: see text] is two less than that of [Formula: see text] whenever [Formula: see text] and [Formula: see text] are two adjacent vertices of [Formula: see text].
R. Dharmarajan, D. Ramachandran
openaire   +2 more sources

Conjectural Criticism on Virgil

2013
exaly   +2 more sources

Minkowsky's conjecture on the critical determinant

Cybernetics, 1986
The authors investigate Minkowski's famous conjecture on the critical determinant of the domain \(| x|^ p+| y|^ p1\) with the help of a computer. They show that their computer-results support Minkowski's conjecture in particular at the critical regions \(p=1+\epsilon_ 1\) and \(p=2\pm \epsilon_ 2\) for small \(\epsilon_ 1,\epsilon_ 2>0\).
Glazunov, N. M., Malyshev, A. V.
openaire   +1 more source

The rise and fall of the critical graph conjecture

Journal of Graph Theory, 1983
AbstractIn this expository paper we discuss the critical graph conjecture and its eventual disproof by M.K. Goldberg and others.
Amanda G. Chetwynd, Robin J. Wilson
openaire   +2 more sources