Results 231 to 240 of about 1,526,980 (375)

Asymmetric Conjugate Hydrocyanation of α,β-Unsaturated Aldehydes Catalyzed by Engineered 2-Deoxy-D-ribose-5-phosphate Aldolase. [PDF]

Chemistry
Zhou H, Fodran P, Fu H, Poelarends GJ.
europepmc   +1 more source

Tuning redox behavior and emissive wavelength of conjugated polymers by p–n diblock structures — a theoretical investigation

, 2000
Jing-Fang Pan, Soo-Jin Chua, Wei Huang
openalex   +2 more sources

Small-Format Drug Conjugates: A Viable Alternative to ADCs for Solid Tumours? [PDF]

, 2018
Mahendra P. Deonarain, Gökhan Yahioglu, Ioanna Stamati, Anja Pomowski, James Clarke, Bryan Edwards, Soraya Diez-Posada, Ashleigh C. Stewart   +7 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

A Bifunctional Antibody Conjugate for Marking the Location of DNA Binding Proteins on DNA Fibers. [PDF]

ACS Omega
Pokharel D, Shaik A, Gali H, Ling C, Bellani MA, Seidman MM.   +5 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Nanogold-Lateral Flow Assay for Ginseng DNA Differentiation. [PDF]

Biosensors (Basel)
Tiffere AH, Sojoudi P, Oberc C, Li PCH.
europepmc   +1 more source

PIN16 COMPARATIVE CRITICAL REVIEW OF COST-EFFECTIVENESS TOOLS OF PNEUMOCOCCAL CONJUGATE VACCINE (PCV)

, 2010
Nathorn Chaiyakunapruk, Ratchadaporn Somkrua, Raymond Hutubessy, AMH Restrepo, Alessia Melegaro, John Edmunds, Philippe Beutels   +6 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Nanobody-drug conjugates for targeting specific GPCR pairs. [PDF]

PLoS Biol
Huang X, Roth BL.
europepmc   +1 more source