Results 61 to 70 of about 1,470,980 (359)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Human Serum Albumin Grafted by Monomeric and Polymeric β-Cyclodextrin as Drug Delivery System for Levofloxacin with Improved Pharmacological Properties

Future Pharmacology
Human serum albumin (HSA) is a multifunctional protein, known to be a natural carrier for a number of endogenous and exogenous compounds, including drugs.
Tatiana Yu Kopnova, Linara R. Yakupova, Natalya Georgievna Belogurova, Elena Vadimovna Kudryashova   +3 more
doaj   +1 more source

SYNTHETIC CONJUGATED ANALOGUES OF CAPSULE POLYSACCHARIDES OF PNEUMOCOCCUS - AN INSTRUMENT FOR DETECTION OF POST-VACCINATION ANTIBODIES

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Evaluation of the ability of capsule polysaccharides (CP) of Streptococcus pneumoniae serotype 3 and 14 and their synthetic structure analogues, conjugated with bovine serum albumin (BSA), to detect antibodies in post-vaccination sera of mice ...
E. A. Kurbatova, E. A. Akhmatova, N. K. Akhmatova, N. B. Egorova, N. E. Yastrebova, E. V. Sukhova, Yu. E. Tsvetkov, D. V. Yashunsky, N. E. Nifantiev   +8 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Hermitian conjugate measurement

, 2009
We propose a new class of probabilistic reversing operations on the state of a system that was disturbed by a weak measurement. It can approximately recover the original state from the disturbed state especially with an additional information gain using ...
C. H. Bennett, Hiroaki Terashima, L. D. Landau, M. A. Nielsen, M. Ueda, Masahito Ueda, S. Wu   +6 more
core   +1 more source

Boosting Photocatalytic Performance of ZnO Nanowires via Building Heterojunction with Conjugated 2,4,6-Triaminopyrimidine-g-C₃N₄

Molecules
Photocatalysis is one of the most effective ways to solve environmental problems by solving pollutants. This article designed and prepared a conjugated system of 2,4,6-triaminopyrimidine-g-C3N4 (TAP-CN) to modify ZnO NWs.
Jiahui Lou, Lihong Wang, Yaqiong Huang, Jun Xing, Xiaojie Yang   +4 more
doaj   +1 more source

Biosynthesis and Characterization of Zearalenone-14-Sulfate, Zearalenone-14-Glucoside and Zearalenone-16-Glucoside Using Common Fungal Strains

Toxins, 2018
Zearalenone (ZEN) and its phase II sulfate and glucoside metabolites have been detected in food and feed commodities. After consumption, the conjugates can be hydrolyzed by the human intestinal microbiota leading to liberation of ZEN that implies an ...
Antje Borzekowski, Tatjana Drewitz, Julia Keller, Dietmar Pfeifer, Hans-Jörg Kunte, Matthias Koch, Sascha Rohn, Ronald Maul   +7 more
doaj   +1 more source

Conjugation in semigroups

Journal of Algebra, 2014
The action of any group on itself by conjugation and the corresponding conjugacy relation play an important role in group theory. There have been several attempts to extend the notion of conjugacy to semigroups. In this paper, we present a new definition of conjugacy that can be applied to an arbitrary semigroup and it does not reduce to the universal ...
António Malheiro, António Malheiro, Janusz Konieczny, João Araújo, João Araújo   +4 more
openaire   +3 more sources

Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide.

Journal of the American Chemical Society, 2016
Bacterial infection caused by intracellular pathogens, such as Mycobacterium, Salmonella, and Brucella, is a burgeoning global health epidemic that necessitates urgent action.
Anna Brezden, M. F. Mohamed, M. Nepal, J. Harwood, Jerrin Kuriakose, M. Seleem, J. Chmielewski   +6 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source