Results 261 to 270 of about 100,362 (316)

An overview of the clinical development of the 20-valent pneumococcal conjugate vaccine in adults. [PDF]

Hum Vaccin Immunother
McElwee K, Vojicic J, Sabharwal C, Ginis J, Peng Y, Mircus G, Watson W, Anderson A.   +7 more
europepmc   +1 more source

Low-Cost Integrated Optical Microscope and Contact-Mode Atomic Force Microscope System Based on DVD Optical Pickup Unit. [PDF]

Sensors (Basel)
Wang L, Dong C, Jin Y, Lu Z, Lu YQ, Zhang W.   +5 more
europepmc   +1 more source

Weaknesses out of strength: PNA against the penicillin-binding proteins. [PDF]

Mol Ther Nucleic Acids
Wdowiak M.
europepmc   +1 more source

Challenges and Opportunities for Cleavable Linkers Used in Polymer-Drug Conjugates. [PDF]

J Am Chem Soc
Karimi F, Locock KES, Chiefari J, Williams CC, Blackman LD.   +4 more
europepmc   +1 more source

Invasive Pneumococcal Disease Epidemiology and Conjugate Vaccines in Canada, 2000-2019.

JAMA Netw Open
Ramos B, Vadlamudi NK, Golden AR, Martin I, Tyrrell G, Brousseau N, Sadarangani M, Canadian Immunization Research Network.   +7 more
europepmc   +1 more source

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Ramoplanin Imaging Conjugates – Synthesis and Evaluation

Medicinal Chemistry, 2013
In a previous study we found that fluorescence-marked vancomycin--a glycopeptide antibiotic--is taken up into human tumor cells. To expand on these investigations we now used the lipoglycodepsipeptide antibiotic ramoplanin. Compared to vancomycin it is not only a bigger molecule, but it also has two potential binding sites for coupling to the imaging ...
Sheikh, Sumbla, Sturzu, Alexander, Kalbacher, Hubert, Klose, Uwe, Amin, Bushra, Deeg, Martin, Ernemann, Ulrike, Heckl, Stefan, Nägele, Thomas, Horger, Marius   +9 more
openaire   +3 more sources

Comparative evaluation of cytotoxicity of a glucosamine-TBA conjugate and a chitosan-TBA conjugate

International Journal of Pharmaceutics, 2004
D-glucosamine and chitosan were modified by the immobilization of thiol groups utilizing 2-iminothiolane. The toxicity profile of the resulting D-glucosamine-TBA (4-thiobutylamidine) conjugate, of chitosan-TBA conjugate and of the corresponding unmodified controls was evaluated in vitro.
Davide, Guggi, Nina, Langoth, Martin H, Hoffer, Michael, Wirth, Andreas, Bernkop-Schnürch   +4 more
openaire   +2 more sources

A Scheme for the Evaluation of Electron Delocalization and Conjugation Efficiency in Linearly π-Conjugated Systems

Journal of Chemical Theory and Computation, 2009
In this study, we present a scheme for the evaluation of electron delocalization and conjugation efficiency in lineraly pi-conjugated systems. The scheme, based on the natural bond orbital theory, allows monitoring the evolution of electron delocalization along an extended conjugation path as well as its response to chemical modification.
BRUSCHI, MAURIZIO, Limacher, PA, Hutter, J, Luethi HP   +3 more
openaire   +4 more sources

Streptavidin conjugation and quantification—a method evaluation for nanoparticles

Analytical and Bioanalytical Chemistry, 2016
Aiming at the development of validated protocols for protein conjugation of nanomaterials and the determination of protein labeling densities, we systematically assessed the conjugation of the model protein streptavidin (SAv) to 100-, 500-, and 1000-nm-sized polystyrene and silica nanoparticles and dye-encoded polymer particles with two established ...
Pablo Darío, Quevedo, Thomas, Behnke, Ute, Resch-Genger   +2 more
openaire   +2 more sources