Results 1 to 10 of about 824,265 (188)
New modification of the hestenes-stiefel with strong wolfe line search [PDF]
, 2021 . The method of the nonlinear conjugate gradient is widely used in solving large-scale unconstrained optimization since been proven in solving optimization problems without using large memory storage.
Basri, Srimazzura +2 more
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Types of Conjugal Networks, Conjugal Conflict and Conjugal Quality [PDF]
European Sociological Review, 2004 This article considers how various configurations of network characteristics affect conjugal quality. To investigate this issue, we use data from a large survey on conjugal functioning, based on 910 married couples with co-resident children living in Switzerland. Using reports from both male and female partners, we first empirically define six types of
Widmer, E., Kellerhals, J., Levy, R.
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Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery
Pharmaceutics, 2021 The treatment of retinal diseases by intravitreal injections requires frequent administration unless drug delivery systems with long retention and controlled release are used.
Eva Kicková +13 more
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Twenty Years of Research on Cyclodextrin Conjugates with PAMAM Dendrimers
Pharmaceutics, 2021 Recently, the number of gene and oligonucleotide drugs are increasing. Of various drug delivery systems (DDSs) for gene and oligonucleotide drugs, few examples of the clinical application of polymer as drug carriers are known, despite development of the ...
Hidetoshi Arima
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Molecules, 2023 In the search for crop protectants, amino acid ester conjugates have been widely investigated as potential antifungal agents. In this study, a series of rhein–amino acid ester conjugates were designed and synthesized in good yields, and their structures ...
Shunshun Chen +8 more
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Novel G‐CSF conjugated anionic globular dendrimer: Preparation and biological activity assessment
Pharmacology Research & Perspectives, 2021 The most crucial role of granulocyte colony‐stimulating factor (G‐CSF) in the body is to increase the strength of immune system. In recent years, research on the use of nanoparticles in pharmaceuticals has been considered, most of which have been for ...
Seyed Shahaboddin Mousavi Motlagh +7 more
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Molecules, 2022 Oligonucleotides with an amino linker at the 3′-end are useful for the preparation of conjugated oligonucleotides. However, chemically modified nucleosides, which are unstable under basic conditions, cannot be incorporated into oligonucleotides using the
Takashi Osawa, Qin Ren, Satoshi Obika
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Drug Delivery, 2023 Most chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks.
Peng Dong +8 more
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On Functions with a Conjugate [PDF]
Annales de l'Institut Fourier, 2015 Harmonic functions of two variables are exactly those that admit a conjugate, namely a function whose gradient has the same length and is everywhere orthogonal to the gradient of the original function. We show that there are also partial differential equations controlling the functions of three variables that admit a conjugate.
Baird, Paul, Eastwood, Michael
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Cells, 2020 Clostridioides difficile (CD) is a Gram-positive pathogen responsible for CD-associated disease (CDAD), which is characterized by symptoms ranging from mild diarrhea to pseudomembranous colitis.
Katarzyna Pacyga +7 more
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