Results 11 to 20 of about 404,179 (310)

Conjugate vaccines [PDF]

open access: yesArchives of Disease in Childhood, 2005
A, Finn, P, Heath
openaire   +4 more sources

Improvement of conjugate gradient methods for removing impulse noise images [PDF]

open access: yes, 2023
Optimization problems occur in most disciplines like engineering, physics, mathematics, economics, administration, commerce, social sciences, and even politics.
Ahmed A. Abdullah, Ali   +3 more
core   +1 more source

Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: a cross-sectional study [PDF]

open access: yes, 2011
We investigated the effect of the 7-valent pneumococcal conjugate vaccine (PCV7) programme in England on serotype-specific carriage and invasive disease to help understand its role in serotype replacement and predict the impact of higher valency vaccines.
Andrews, Nick   +24 more
core   +5 more sources

Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery

open access: yesPharmaceutics, 2021
The treatment of retinal diseases by intravitreal injections requires frequent administration unless drug delivery systems with long retention and controlled release are used.
Eva Kicková   +13 more
doaj   +1 more source

Twenty Years of Research on Cyclodextrin Conjugates with PAMAM Dendrimers

open access: yesPharmaceutics, 2021
Recently, the number of gene and oligonucleotide drugs are increasing. Of various drug delivery systems (DDSs) for gene and oligonucleotide drugs, few examples of the clinical application of polymer as drug carriers are known, despite development of the ...
Hidetoshi Arima
doaj   +1 more source

Rhein–Amino Acid Ester Conjugates as Potential Antifungal Agents: Synthesis and Biological Evaluation

open access: yesMolecules, 2023
In the search for crop protectants, amino acid ester conjugates have been widely investigated as potential antifungal agents. In this study, a series of rhein–amino acid ester conjugates were designed and synthesized in good yields, and their structures ...
Shunshun Chen   +8 more
doaj   +1 more source

Novel G‐CSF conjugated anionic globular dendrimer: Preparation and biological activity assessment

open access: yesPharmacology Research & Perspectives, 2021
The most crucial role of granulocyte colony‐stimulating factor (G‐CSF) in the body is to increase the strength of immune system. In recent years, research on the use of nanoparticles in pharmaceuticals has been considered, most of which have been for ...
Seyed Shahaboddin Mousavi Motlagh   +7 more
doaj   +1 more source

Development of Phosphoramidite Reagents for the Synthesis of Base-Labile Oligonucleotides Modified with a Linear Aminoalkyl and Amino-PEG Linker at the 3′-End

open access: yesMolecules, 2022
Oligonucleotides with an amino linker at the 3′-end are useful for the preparation of conjugated oligonucleotides. However, chemically modified nucleosides, which are unstable under basic conditions, cannot be incorporated into oligonucleotides using the
Takashi Osawa, Qin Ren, Satoshi Obika
doaj   +1 more source

Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells

open access: yesDrug Delivery, 2023
Most chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks.
Peng Dong   +8 more
doaj   +1 more source

Types of Conjugal Networks, Conjugal Conflict and Conjugal Quality [PDF]

open access: yesEuropean Sociological Review, 2004
This article considers how various configurations of network characteristics affect conjugal quality. To investigate this issue, we use data from a large survey on conjugal functioning, based on 910 married couples with co-resident children living in Switzerland. Using reports from both male and female partners, we first empirically define six types of
Widmer, E., Kellerhals, J., Levy, R.
openaire   +3 more sources

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