Results 151 to 160 of about 148,341 (304)

Synthesis, Characterisation and Preliminary Antimicrobial Evaluation of Chitosan-4-Anisaldehyde Conjugates. [PDF]

Polymers (Basel)
Makhayeva DN, Mukhamediya DD, Tairova SR, Jumagaziyeva A, Irmukhametova GS, Khutoryanskiy VV.   +5 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Toward Universal Protection: A Comprehensive Review of Pneumococcal Disease, Emerging Vaccination Challenges and Future Perspectives. [PDF]

Vaccines (Basel)
Sgrulletti M, Mastrototaro MF, Beni A, Mantuano G, Costagliola G, Santilli V, Montin D, Rizzo C, Martire B, Marseglia GL, Miraglia Del Giudice M, Moschese V, Italian Society of Pediatric Allergy, Immunology Siaip Vaccine Committee.   +13 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Reactivity of Antibodies Immobilized on Gold Nanoparticles: Fluorescence Quenching Study. [PDF]

Molecules
Sotnikov DV, Agapov AS, Zherdev AV, Dzantiev BB.   +3 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Conjugate Gradients and Conjugate Residuals type methods for solving Least Squares problems from Tomography

, 2012
Teun Kloek
openalex   +2 more sources

A Numerical Investigation on the Influence of Film-Cooling Hole Inclination Angle on the Stress Field of Surrounding Thermal Barrier Coating. [PDF]

Materials (Basel)
Shi Z, Jia Y, He X, Tian Z, Liu Y.
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Towards Heart Rate Estimation in Complex Multi-Target Scenarios: A High-Precision FMCW Radar Scheme Integrating HDBS and VLW. [PDF]

Sensors (Basel)
Dong X, Liu Y, Wang J, Wu S, Wang C, Tang S.   +5 more
europepmc   +1 more source