Results 81 to 90 of about 148,341 (304)

Detecting Weak Underwater Targets Using Block Updating of Sparse and Structured Channel Impulse Responses

Remote Sensing
In this paper, we considered the real-time modeling of an underwater channel impulse response (CIR), exploiting the inherent structure and sparsity of such channels.
Chaoran Yang, Qing Ling, Xueli Sheng, Mengfei Mu, Andreas Jakobsson   +4 more
doaj   +1 more source

Over-constrained Weierstrass iteration and the nearest consistent system

, 2014
We propose a generalization of the Weierstrass iteration for over-constrained systems of equations and we prove that the proposed method is the Gauss-Newton iteration to find the nearest system which has at least $k$ common roots and which is obtained ...
Ruatta, Olivier, Sciabica, Mark, Szanto, Agnes   +2 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Preconditioned Minimal Residual Methods for Chebyshev Spectral Caluclations [PDF]

The problem of preconditioning the pseudospectral Chebyshev approximation of an elliptic operator is considered. The numerical sensitiveness to variations of the coefficients of the operator are investigated for two classes of preconditioning matrices ...
Canuto, C., Quarteroni, A.
core   +1 more source

Multigrid Algorithms for Domain-Wall Fermions

, 2012
We describe an adaptive multigrid algorithm for solving inverses of the domain-wall fermion operator. Our multigrid algorithm uses an adaptive projection of near-null vectors of the domain-wall operator onto coarser four-dimensional lattices.
Brower, R. C., Clark, M. A., Cohen, Saul D., Osborn, J. C.   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Some Preconditioning Techniques for Saddle Point Problems [PDF]

, 2006
Saddle point problems arise frequently in many applications in science and engineering, including constrained optimization, mixed finite element formulations of partial differential equations, circuit analysis, and so forth.
Benzi, Michele, Wathen, A. J.
core   +1 more source

Phase Retrieval with Random Phase Illumination

, 2012
This paper presents a detailed, numerical study on the performance of the standard phasing algorithms with random phase illumination (RPI). Phasing with high resolution RPI and the oversampling ratio $\sigma=4$ determines a unique phasing solution up to ...
Albert Fannjiang, Almoro, Anand, Bauschke, Fannjiang, Fienup, Fienup, Fienup, Gerchberg, Hayes, Hayes, Levi, Marchesini, Miao, Miao, Miao, Miao, Miao, Millane, Pitts, Wenjing Liao   +20 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source