Results 231 to 240 of about 1,081,297 (374)

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

An assessment of the value of Haemophilus influenzae type b conjugate vaccine in Asia

, 1998
Mark A. Miller
openalex   +1 more source

Conjugate Vaccine Immunotherapy for Substance Use Disorder

Pharmacological Reviews, 2017
Paul T. Bremer, K. Janda
semanticscholar   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

Comparative immune response of Typbar TCV® (typhoid conjugate vaccine) in extremes of age: An Indian experience. [PDF]

Hum Vaccin Immunother
Vadrevu KM, Chiteti SR, Dugyala R, Aileni VK, Kunta A, Patnaik BN, Ella R.   +6 more
europepmc   +1 more source

The lights went out.

, 2012
Cavelaars, Chen, Cholesterol Treatment Trialists' Ctt Collaboration, Kromhout, Kunitz, Leon, S. Ebrahim, Uusitalo   +7 more
core   +1 more source

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

Advanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan, Ming Cai, Yiyu Wang, Hong‐Hui Wang, Zhou Nie   +4 more
wiley   +1 more source

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) Administered with Routine Pediatric Vaccines: A European Randomized Controlled Trial. [PDF]

Infect Dis Ther
Martinon-Torres F, Virta MM, Koski S, de la Cueva IS, Szymanski HT, Bosis S, Drăgănescu AC, Silfverdal SA, Zambrano B, Dhingra MS, B'Chir S, Syrkina O, Lyabis O, Vasquez GA, Rehm C, MET58 Study Group.   +15 more
europepmc   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

The impact of 10-valent pneumococcal conjugate vaccine on the incidence of admissions to hospital with hypoxaemic and non-hypoxaemic pneumonia in Kenyan children. [PDF]

PLOS Glob Public Health
Haeusler IL, Kagucia EW, Bottomley C, Otiende M, Nyiro J, Scott JAG.   +5 more
europepmc   +1 more source