Results 241 to 250 of about 53,707 (310)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine Versus a 13-Valent Vaccine in Infants: A Systematic Review and Meta-Analysis. [PDF]

Vaccines (Basel)
Pacheco-Haro MD, de Arenas-Arroyo SN, Díaz-Goñi V, Velasco-Lucio EJ, Castellares-González CI, Reynolds-Cortez V, Simeón-Prieto A, Ignateva E, Martínez-Vizcaíno V.   +8 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in Hong Kong - A retrospective database study. [PDF]

Hum Vaccin Immunother
Yu Q, Chui CSL, Yeo SH, Patel D, Lim CTK, Li X, Chan VKY, Yamada E, Sukarom I.   +8 more
europepmc   +1 more source

Evaluation of efficacy and effectiveness across the pneumococcal conjugate vaccine era. [PDF]

Hum Vaccin Immunother
LaFon DC.
europepmc   +1 more source

Cross reactivity within pneumococcal serogroups 6 and 15 following adult vaccination with pneumococcal conjugate vaccine V116. [PDF]

Commun Med (Lond)
Li J, Platt HL, Hu W, Xu W, Chapman TJ, Nolan KM, Hartzel J, Buchwald UK.   +7 more
europepmc   +1 more source

A Phase III Clinical Trial of Immunogenicity and Safety of Meningococcal A and C Polysaccharide Conjugate Vaccine in Infants Aged 3-5 Months. [PDF]

Vaccines (Basel)
Shi L, Zhang Z, Liu Y, Li M, Lu W, Yang Y, Zhao D, Wang B, Fang W.   +8 more
europepmc   +1 more source

The effectiveness of pneumococcal conjugate vaccine: an UK experience

, 2012
Wong, ICK
core