Results 21 to 30 of about 53,707 (310)

Dose-specific efficacy of Haemophilus influenzae type b conjugate vaccines: a systematic review and meta-analysis of controlled clinical trials. [PDF]

, 2012
Global coverage of infant Haemophilus influenzae type b (Hib) vaccination has increased considerably during the past decade, partly due to GAVI Alliance donations of the vaccine to low-income countries. In settings where large numbers of children receive
Clark, A, Mulholland, KE, Griffiths, UK, Miners, A, Gessner, B, Sanderson, C, Sedyaningsih, ER   +6 more
core   +1 more source

Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa.

PLoS ONE, 2013
BackgroundThe meningococcal serogroup A (MenA) polysaccharide conjugate vaccine used in Sub-Saharan Africa does not prevent disease caused by MenW or MenX strains, which also cause epidemics in the region.
Rolando Pajon, Andrew M Fergus, Dan M Granoff   +2 more
doaj   +1 more source

Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making tools. [PDF]

, 2011
BACKGROUND: Several decision support tools have been developed to aid policymaking regarding the adoption of pneumococcal conjugate vaccine (PCV) into national pediatric immunization programs.
A.M. Henao, Henao, Ana Maria, J. Hombach, Hutubessy, Raymond, Edmunds, John W, Beutels, Philippe, Joachim Hombach, Hutubessy Raymond, R. Somkrua, Chaiyakunapruk, Nathorn, Hombach, Joachim, R. Hutubessy, John W Edmunds, Ana Maria Henao, Philippe Beutels, Hombach Joachim, Nathorn Chaiyakunapruk, Henao Ana Maria, Edmunds John W, P. Beutels, Somkrua, Ratchadaporn, Edmunds, John W., Melegaro, Alessia, N. Chaiyakunapruk, Ratchadaporn Somkrua, Chaiyakunapruk Nathorn, Beutels Philippe, Raymond Hutubessy, Melegaro Alessia, Somkrua Ratchadaporn, Alessia Melegaro, W.J. Edmunds   +31 more
core   +1 more source

Changes in serogroup and genotype prevalence among carried meningococci in the United Kingdom during vaccine implementation [PDF]

, 2011
Natural fluctuations in carried meningococcal genotypes and phenotypes a can be affected by the use of conjugate vaccines, and not all of these changes are anticipatable in advance of vaccine ...
McCarthy, Noel D., Maclennan, Jenny, Evans, Meirion R, Rachel Urwin, Cameron, J. Claire, Neal, Keith R, Ibarz-Pavón, AB, Nicholas J. Andrews, Stuart C. Clarke, Cann, Kathryn, Maiden, MC, Noel D. McCarthy, Cameron, JC, Evans, MR, Maiden, Martin, James M. Stuart, Harrison, S, Ala'aldeen, Dlawer, Cunningham, Richard, Martin C. J. Maiden, Jolley, Keith A, Derrick W. Crook, Dlawer Ala'Aldeen, Walker, AM, Baxter, David, Gray, Stephen J., Urwin, R, Crook, Derrick W., Keith R. Neal, Clarke, SC, Clarke, Stuart C, Maiden, Martin C. J., Jolley, Keith A., Stuart, James M., Maiden, Martin CJ, Maclennan, J, Keith A. Jolley, Kaczmarski, E, Walker, A. Mark, J. Simon Kroll, Richard Cunningham, Andrews, NJ, J. Claire Cameron, Crook, DW, Evans, Meirion Rhys, Harrison, Sarah, Andrews, Nicholas J, Ala'aldeen, D, Edward Kaczmarski, Baxter, D, McCarthy, Noel D, Cann, K, Crook, Derrick W, Kathryn Cann, Ibarz-Pavón, Ana Belén, Clarke, Stuart C., Evans, Meirion R., A. Mark Walker, Cunningham, R, Kroll, J. Simon, Kroll, J Simon, Neal, KR, Cameron, J Claire, Maiden, MCJ, Andrews, Nicholas J., Neal, Keith R., McCarthy, ND, Stephen J. Gray, Jenny MacLennan, Meirion R. Evans, Crook, Derrick, Urwin, Rachel, Stuart, James M, Stuart, JM, Sarah Harrison, Gray, SJ, Gray, Stephen J, Ana Belén Ibarz-Pavón, Walker, A Mark, Kaczmarski, Edward, David Baxter, Andrews, Nicholas J., Kroll, JS, Jolley, KA   +83 more
core   +1 more source

Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity. [PDF]

, 2012
Despite the success of conjugate vaccination against meningococcal group C (MenC) disease, post-vaccination, some individuals still exhibit rapid waning of initially protective bactericidal antibody levels.
Findlow, J., Helen Findlow, Findlow, H., James B Wing, Findlow Jamie, Read, Robert C., Helen Findlow (184554), Read Robert C., Wing, J.B., Borrow, Ray, Heath, A.W., James B. Wing, Robert C. Read (145234), Borrow Ray, Read, R.C., Andrew Lees, Smart Lynne, Borrow, R., Heath, Andrew W., Lynne Smart, Lees, Andrew, Jennifer Carlring, Findlow, Helen, James B. Wing (184537), Wing James B., Findlow, Jamie, Ray Borrow, Robert C. Read, Heath Andrew W., Smart, L., Lees Andrew, Lynne Smart (184541), Ray Borrow (49342), Andrew W. Heath (184566), Jamie Findlow (184547), Smart, Lynne, Lees, A., Andrew Lees (184562), Andrew W Heath, Wing, James B., Andrew W. Heath, Robert C Read, Rachel A Foster, Findlow Helen, Jamie Findlow   +44 more
core   +1 more source

Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine [PDF]

, 2013
Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children.
Nicholas J Loman, Jacqueline Chan, Tocheva Anna S., O’Connor Leigh, Pallen, Mark J., Constantinidou C., Loman, Nicholas J., Pallen M.J., Faust, Saul N, Faust, Saul N., Loman, Nicholas, Clarke S.C., Tocheva A.S., Constantinidou Chrystala, Mark J Pallen, Loman, Nicholas J, Chan, Jacqueline, Constantinidou, Chrystala, Stuart C Clarke, Pallen, Mark J, Gladstone R.A., O'Connor, Leigh, Chrystala Constantinidou, Clarke, Stuart C, Tocheva, Anna S., Faust, S.N., Clarke, S.C., Johanna M C Jefferies, Loman Nicholas J., Faust Saul N., Clarke Stuart C., Gladstone, Rebecca A., Chan J., O’Connor, Leigh, Leigh O'Connor, Anna S Tocheva, Clarke, Stuart C., Pallen, Mark, Tocheva, Anna S, Jefferies J.M.C., Jefferies, Johanna M C, Loman N.J., Chan Jacqueline, Jefferies, Johanna M.C., Gladstone, Rebecca, Saul N Faust, Jefferies Johanna M. C., Jefferies, Johanna M. C., Faust S.N., Pallen Mark J., Gladstone, Rebecca A, Rebecca A Gladstone, O'Connor L., Gladstone Rebecca A.   +53 more
core   +1 more source

Evolution of conjugate vaccines

Expert Review of Vaccines, 2002
Conjugate vaccines--bacterial polysaccharides conjugated to proteins to improve their immunizing properties--have been a success story since their introduction less than 20 years ago. The Haemophilus influenzae type b conjugate vaccine has nearly eliminated invasive Haemophilus influenzae type b disease in large parts of the world.
P Helena, Mäkelä, Helena, Käyhty
openaire   +2 more sources

7-Valent pneumococcal conjugate vaccination in England and Wales: is it still beneficial despite high levels of serotype replacement? [PDF]

, 2011
BACKGROUND: The UK introduced the 7-valent pneumococcal conjugate vaccine (PCV7) into the national vaccination program in September 2006. Previous modelling assumed that the likely impact of PCV7 on invasive pneumococcal disease (IPD) would be similar to
Nigel Gay, Andrews, Nick, George, Robert, Robert George, Gay Nigel, Miller, Elizabeth, George Robert, Pauline A Waight, Miller Elizabeth, Yoon Hong Choi, N. Gay, Choi, Yoon Hong, Pauline A. Waight, Andrews Nick, R. George, Nick Andrews, Waight Pauline A., Jit, Mark, Gay, Nigel, Jit Mark, Y.H. Choi, Choi Yoon Hong, Elizabeth Miller, M. Jit, P.A. Waight, Melegaro, Alessia, E. Miller, Mark Jit, N. Andrews, Waight, Pauline A, Melegaro Alessia, Alessia Melegaro   +31 more
core   +1 more source

Immune persistence of a single dose of 23-valent pneumococcal polysaccharide vaccine: A 6-year follow-up

Human Vaccines & Immunotherapeutics
In a previous phase 3 clinical trial, a 23-valent pneumococcal polysaccharide vaccine (PPV23) induced robust immune responses in participants aged 2 years and older.
Lili Huang, Xinyi Yang, Hong Li, Zhiqiang Xie, Taotao Zhu, Wangyang You, Zeng Wang, Jiebing Tan, Guangwei Feng, Qingmin Sun, Bin Wang, Xing Han, Yanxia Wang   +12 more
doaj   +1 more source

Recommendation for use of the newly introduced pneumococcal protein conjugate vaccines in Korea [PDF]

Korean Journal of Pediatrics, 2011
Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults.
Eun Hwa Choi, Kyung Hyo Kim, Yae Jean Kim, Jong Hyun Kim, Su Eun Park, Hoan Jong Lee, Byung Wook Eun, Dae Sun Jo, Kyong Min Choi, Young Jin Hong   +9 more
doaj   +1 more source