Results 71 to 80 of about 53,707 (310)

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

Typhoid conjugate vaccine implementation in India: A review of supportive evidence

Vaccine: X
Background: Typhoid conjugate vaccines are available in the private market in India and are also recommended by the National Technical Advisory Group on Immunisation (NTAGI) for inclusion in India’s Universal Immunisation Programme in 2022 to control and
Vijayalaxmi V. Mogasale, Anish Sinha, Jacob John, Habib Hasan Farooqui, Arindam Ray, Tracey Chantler, Vittal Mogasale, Bhim Gopal Dhoubhadel, W John Edmunds, Andrew Clark, Kaja Abbas   +10 more
doaj   +1 more source

Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping.

, 2015
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
Gurung, M, Kandasamy, Rama, Neelam Adhikari, David R Murdoch, Katherine A Gould, Murdoch, DR, Thapa, A, Adhikari, N, Hinds, Jason, Shrestha, S, Gould, Katherine A., Anushil Thapa, Kandasamy, R ; https://orcid.org/, Waldron, Denise E., Stephen Thorson, Rama Kandasamy, Waldron, DE, Gould, KA, Ndimah, S, Thorson, Stephen, Kelly, Dominic F., Shrijana Shrestha, Thorson, S, Dominic F Kelly, Meeru Gurung, Thapa, Anushil, Andrew J Pollard, Murdoch, David R., Ndimah, Susan, Shrestha, Shrijana, Denise E Waldron, Hinds, J, Pollard, Andrew J., Kandasamy, R, Adhikari, Neelam, Jason Hinds, Kelly, DF, Gurung, Meeru, Pollard, AJ, Pollard, Andrew, Susan Ndimah   +40 more
core   +1 more source

Chiral Microneedle Arrays With Terahertz Chiroptical Activity With Chiral‐Plasmon‐Chiral‐Phonon Resonance

Advanced Materials, EarlyView.
ABSTRACT Microneedle arrays (MNAs) is a rapidly emerging technology with broad biomedical applications in drug delivery and biosensing. With sub‐millimeter dimensions and periodicity, MNAs possess geometries nearly ideal for biomedical devices operating within the terahertz (THz) spectral window.
Sang Hyun Lee, Hong Ju Jung, John Kim, Bum Chul Park, Caio V. C. R. da Silva, André F. de Moura, Nicholas A. Kotov   +6 more
wiley   +1 more source

An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid, tetanus toxoid, 3-component acellular pertussis, hepatitis B, inactivated poliovirus, and Haemophilus influenzae type b vaccine

, 2013
BACKGROUND: In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines.
Rose, Markus A., William C Gruber, Sherryl Baker, Christine Juergens, Beate Schmoele-Thoma, Gruber, William C., Stefan Zielen, Zielen, Stefan, Jürgens, Christine, Schmoele-Thoma, Beate, Baker, Sherryl, Markus A Rose   +11 more
core   +1 more source

Solid‐State Nanopore Characterization of Dendrimer‐Peptide Conjugates Across Defined Peptide Loadings

Advanced Materials Interfaces, EarlyView.
Solid‐state nanopores are used to interrogate dendrimer‐peptide conjugates with systematically varied peptide loading. Single‐particle ionic current signatures reveal how ligand density modulates deformability, transport pathways, and electromechanical coupling during translocation.
Chaoming Gu, Jin Woong Lee, Kamruzzaman Joty, Marisela Leon, Santosh Khatri, Janeesha Manawasinghe, Seungpyo Hong, Min Jun Kim   +7 more
wiley   +1 more source

Pneumococcal carriage in sub-Saharan Africa--a systematic review. [PDF]

, 2014
BACKGROUND: Pneumococcal epidemiology varies geographically and few data are available from the African continent. We assess pneumococcal carriage from studies conducted in sub-Saharan Africa (sSA) before and after the pneumococcal conjugate vaccine (PCV)
Bottomley, Christian, Andrew Hall, Richard A. Adegbola (20657), Hall, Andrew, Hall Andrew, Effua Usuf (334925), Effua Usuf, Christian Bottomley, Adegbola Richard A., Bottomley Christian, Adegbola, Richard A, Usuf, Effua, Usuf Effua, Andrew Hall (223292), Richard A Adegbola, Christian Bottomley (144483)   +15 more
core   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Molecular shape and immunogenicity of meningococcal polysaccharide group A conjugate vaccine

, 2015
Neisseria meningitidis is a leading cause of severe bacterial infections in infants and young children. As a major virulence factor, meningococcal capsular polysaccharide (PS) is poorly immunogenic and generally does not induce immunological memory ...
Wu, Zhonghua, Xu, Mengfang, Hu, Tao, Du, Yuguang, Xing, Xueqing   +4 more
core   +1 more source