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Conjugate vaccines for enteric fever: proceedings of a meeting organized in New Delhi, India in 2009
Enteric fever is responsible for significant morbidity in South Asia and high prevalence of severe disease is seen in children under two years of age. Effective typhoid vaccines are available, but they cannot be used for children under two years of age
Audino Podda+14 more
doaj +1 more source
Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk of ...
Olivia K Burn+15 more
doaj +1 more source
Challenges to estimating vaccine impact using hospitalization data. [PDF]
Because the real-world impact of new vaccines cannot be known before they are implemented in national programs, post-implementation studies at the population level are critical.
Bruhn, Christian AW+6 more
core +3 more sources
Simultaneous administration of different vaccines is a strategy to increase the possibility to receive vaccines at appropriate age, safely and effectively, reducing the number of sessions and allowing a more acceptable integration of new vaccines into ...
Paolo Bonanni+6 more
doaj +1 more source
The Impact of Vaccination Behavior on Disease Spreading Based on Complex Networks [PDF]
Vaccination is an effective way to prevent and control the occurrence and epidemic of infectious diseases. However, many factors influence whether the residents decide to get vaccinated or not, such as the efficacy and side effects while individuals hope to obtain immunity through vaccination.
arxiv
Conjugate vaccines in which the capsular polysaccharide of Haemophilus influenzae type b, common serotypes of Streptococcus pneumoniae and group C Neisseria meningitidis are covalently bound to a protein antigen to convert a T-cell-independent immune response into a T-cell-dependent response have proved highly effective in the prevention of invasive ...
openaire +2 more sources
Evolution of conjugate vaccines
Conjugate vaccines--bacterial polysaccharides conjugated to proteins to improve their immunizing properties--have been a success story since their introduction less than 20 years ago. The Haemophilus influenzae type b conjugate vaccine has nearly eliminated invasive Haemophilus influenzae type b disease in large parts of the world.
P. Helena Mäkelä, Helena Käyhty
openaire +3 more sources
COVID-19 Vaccine Hesitancy and Information Diffusion: An Agent-based Modeling Approach [PDF]
Despite the unprecedented success in the rapid development of several effective vaccines against the Cov-SARS-2, global vaccination rollout efforts suffer from vaccine distribution inequality and vaccine acceptance, leading to insufficient public immunity provided by the vaccine products.
arxiv
Histo-blood group glycans in the context of personalized medicine [PDF]
Background: A subset of histo-blood group antigens including ABO and Lewis are oligosaccharide structures which may be conjugated to lipids or proteins. They are known to be important recognition motifs not only in the context of blood transfusions, but also in infection and cancer development.
arxiv +1 more source
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]
WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black+21 more
core +2 more sources