Results 21 to 30 of about 347,254 (297)

Promising directions for vaccine development to prevent shigellosis

Биопрепараты: Профилактика, диагностика, лечение, 2022
Shigellosis (bacterial dysentery) is an acute infectious disease caused by Shigella spp., members of the Enterobacteriaceae family. The disease has the highest mortality rate amongst bacterial enteric infections.
M. V. Abramtseva, E. O. Nemanova, N. S. Alekhina   +2 more
doaj   +1 more source

Development of Streptococcus pneumoniae Vaccines Using Live Vectors [PDF]

, 2015
: Streptococcus pneumoniae still causes severe morbidity and mortality worldwide, especially in young children and the elderly. Much effort has been dedicated to developing protein-based universal vaccines to conquer the current shortcomings of capsular ...

core   +1 more source

Progress toward the global control of Neisseria meningitidis: 21st century vaccines, current guidelines, and challenges for future vaccine development

Human Vaccines & Immunotherapeutics, 2018
The control of meningitis, meningococcemia and other infections caused by Neisseria meningitidis is a significant global health challenge. Substantial progress has occurred in the last twenty years in meningococcal vaccine development and global ...
A. W. Dretler, N. G. Rouphael, D. S. Stephens   +2 more
doaj   +1 more source

Cost-effectiveness of Haemophilus influenzae type b conjugate vaccine in low- and middle-income countries: regional analysis and assessment of major determinants. [PDF]

, 2013
OBJECTIVES: To estimate the cost-effectiveness of Haemophilus influenzae type b (Hib) conjugate vaccine in low- and middle-income countries and identify the model variables, which are most important for the result.
Clark, Andrew, Griffiths, Ulla Kou, Hajjeh, Rana   +2 more
core   +1 more source

Conjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques

npj Vaccines, 2023
An effective HIV-1 vaccine remains a critical unmet need for ending the AIDS epidemic. Vaccine trials conducted to date have suggested the need to increase the durability and functionality of vaccine-elicited antibodies to improve efficacy.
Danielle Nettere, Shakthi Unnithan, Nicole Rodgers, Junsuke Nohara, Paul Cray, Madison Berry, Caroline Jones, Lawrence Armand, Shuk Hang Li, Stella J. Berendam, Genevieve G. Fouda, Derek W. Cain, Taylor N. Spence, Joshua A. Granek, Clemontina A. Davenport, Robert J. Edwards, Kevin Wiehe, Koen K. A. Van Rompay, M. Anthony Moody, Sallie R. Permar, Justin Pollara   +20 more
doaj   +1 more source

Vaccination of risk groups in England using the 13 valent pneumococcal conjugate vaccine: economic analysis. [PDF]

, 2012
OBJECTIVE: To estimate the cost effectiveness of vaccinating people with high risk conditions against invasive pneumococcal disease using the 13 valent pneumococcal conjugate vaccine.
Edmunds, W. John, van Hoek, Albert Jan, Trotter, Caroline L, Rozenbaum, Mark H., C. L. Trotter, Miller, Elizabeth, Rozenbaum, Mark H, D. Fleming, Trotter, Caroline L., E. Miller, M. H. Rozenbaum, Edmunds, W John, W. J. Edmunds, Fleming, Douglas, A. J. van Hoek   +14 more
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ANTIGENIC ACTIVITY ASSAYS OF EXPERIMENTAL CONJUGATE VACCINES BASED ON SYNTHETIC OLIGOSACCHARIDE LIGANDS AND CRM197 CARRIER PROTEIN

Медицинская иммунология, 2017
So far, there is no effective treatment for a number of socially significant bacterial and fungal diseases. β-(1→3) glucans are polysaccharides consisting of glucose units linked together with β-(1→3)- glycoside bonds.
E. G. Bogomolova, O. A. Dodrovolskaya, E. A. Fedorova, A. M. Kondrashkina, N. N. Kolmakov, S. A. Ishchuk, I. V. Dukhovlinov, A. S. Simbirtsev   +7 more
doaj   +1 more source

Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity. [PDF]

, 2012
Despite the success of conjugate vaccination against meningococcal group C (MenC) disease, post-vaccination, some individuals still exhibit rapid waning of initially protective bactericidal antibody levels.
Findlow, J., Helen Findlow, Findlow, H., James B Wing, Findlow Jamie, Read, Robert C., Helen Findlow (184554), Read Robert C., Wing, J.B., Borrow, Ray, Heath, A.W., James B. Wing, Robert C. Read (145234), Borrow Ray, Read, R.C., Andrew Lees, Smart Lynne, Borrow, R., Heath, Andrew W., Lynne Smart, Lees, Andrew, Jennifer Carlring, Findlow, Helen, James B. Wing (184537), Wing James B., Findlow, Jamie, Ray Borrow, Robert C. Read, Heath Andrew W., Smart, L., Lees Andrew, Lynne Smart (184541), Ray Borrow (49342), Andrew W. Heath (184566), Jamie Findlow (184547), Smart, Lynne, Lees, A., Andrew Lees (184562), Andrew W Heath, Wing, James B., Andrew W. Heath, Robert C Read, Rachel A Foster, Findlow Helen, Jamie Findlow   +44 more
core   +2 more sources

Decrease in Pneumococcal Co-Colonization following Vaccination with the Seven-Valent Pneumococcal Conjugate Vaccine [PDF]

, 2012
Understanding the epidemiology of pneumococcal co-colonization is important for monitoring vaccine effectiveness and the occurrence of horizontal gene transfer between pneumococcal strains.
Sá-Leão, Raquel, Katherine Gould, Francisco Pinto (188116), Katherine Gould (188123), Hinds, Jason, Pinto, Francisco, Kathrin Mühlemann (109266), Jason Hinds (41307), Silvio D. Brugger, Raquel Sá-Leão (188130), Carina Valente, Kathrin Mühlemann, Gould, K, Valente, C, Brugger, Silvio D., Hermínia de Lencastre, Carina Valente (188109), de Lencastre, Hermínia, Raquel Sá-Leão, Silvio D Brugger, Valente, Carina, Hinds, J, Silvio D. Brugger (109258), Pinto, F, de Lencastre, H, Sá-Leão, R, Brugger, SD, Jason Hinds, Francisco Pinto, Mühlemann, K, Hermínia de Lencastre (1970), Gould, Katherine, Mühlemann, Kathrin   +32 more
core   +2 more sources

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., del Campo, J., Zayas, C., Cuello, M., Romeu, B., Ferro, Valerie A., Gonzales, E., Cabrera, O., Balbao, J.   +8 more
core   +4 more sources