Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Synthesis and characterization of novel low band gap semiconducting polymers for organic photovoltaic and organic field effect transistor applications [PDF]
, 2012 PhDThis thesis describes the synthesis, characterization and device properties of a range of conjugated polymers incorporating 3,6-dilakylthieno[3,2-b]thiophene.
Aleroh, Dickson
core
Electronic Properties of Topological Materials: Optical Excitations in Moebius Conjugated Polymers
, 2004 Electronic structures and optical excitations in Moebius conjugated polymers are studied theoretically. Periodic and Moebius boundary conditions are applied to the tight binding model of poly(para-phenylene), taking exciton effects into account.
Ajami D. +11 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Transforming protein-polymer conjugate purification by tuning protein solubility
Nature Communications, 2019 Therapeutic proteins are often conjugated with polymers, but separating the conjugate from unconjugated protein and free polymer is a major challenge.
Stefanie L. Baker +9 more
doaj +1 more source
Raman Spectroscopy and DFT calculations for the Electronic Structure Characterization of Conjugated Polymers [PDF]
, 2016 Flash presentationIn the last three decades, there has been a broad academic and industrial interest in conjugated polymers as semiconducting materials for organic electronics.
González Cano, Rafael Carlos +2 more
core
\u3a0\u2011Stacking Signature in NMR Solution Spectra of Thiophene-Based Conjugated Polymers [PDF]
, 2017 Studies on conjugated polymers seldom report on their NMR characterization in solution. This paper shows how NMR experiments, both 1H NMR and routine 2D NMR spectra, can help in gaining a further insight into the aggregation behavior of conjugated ...
Lanzi, Massimiliano +4 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Fast and Selective Post-polymerization Modification of Conjugated Polymers Using Dimethyldioxirane
Frontiers in Chemistry, 2019 Modification of functional groups attached to conjugated polymer backbones can drastically alter the material properties. Oxidation of electron-donating thioalkyl substituents to electron-withdrawing sulfoxides or sulfones is a particularly effective ...
Emmanuel Reichsöllner +7 more
doaj +1 more source
Electronic Excitations and Insulator-Metal Transition in Poly(3-hexylthiophene) Organic Field-Effect Transistors [PDF]
, 2006 We carry out a comprehensive theoretical and experimental study of charge injection in Poly(3-hexylthiophene) (P3HT) to determine the most likely scenario for metal-insulator transition in this system.
D. Baeriswyl +7 more
core +2 more sources