Results 51 to 60 of about 176,805 (298)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

High-mobility, trap-free charge transport in conjugated polymer diodes

open access: yesNature Communications, 2019
Charge transport in organic diodes based on conjugated polymers is severely limited by the high water-related trap concentration and energetic disorder. Here, the authors report high-mobility trap-free charge transport in low-disorder conjugated polymers
Mark Nikolka   +13 more
doaj   +1 more source

Sequencing conjugated polymers by eye [PDF]

open access: yesScience Advances, 2018
Electrospray deposition and STM as a new analytical technique to sequence conjugated polymers and reveal polymerization defects.
Warr, Daniel A.   +8 more
openaire   +3 more sources

Nonlinear optical response in doped conjugated polymers

open access: yes, 1995
Exciton effects on conjugated polymers are investigated in soliton lattice states. We use the Su-Schrieffer-Heeger model with long-range Coulomb interactions.
Bloembergen N   +6 more
core   +1 more source

Polymer nanofibers as novel light-emitting sources and lasing material [PDF]

open access: yes, 2013
Polymer micro- and nano-fibers, made of organic light-emitting materials with optical gain, show interesting lasing properties. Fibers with diameters from few tens of nm to few microns can be fabricated by electrospinning, a method based on electrostatic
Camposeo, Andrea   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Post-polymerisation functionalisation of conjugated polymer backbones and its application in multi-functional emissive nanoparticles

open access: yesNature Communications, 2018
Functionalisation of conjugated polymers is essential for performance in many applications, yet there are limited approaches to achieve this. Here the authors developed a method for the direct postpolymerisation modification of the aromatic backbone of ...
Adam Creamer   +15 more
doaj   +1 more source

Recent advances in conjugated polythiophene-based rod–rod block copolymers: From morphology control to optoelectronic applications

open access: yesGiant, 2020
Conjugated rod-rod block copolymers (BCPs) have attracted considerable attention during the past decade as they possess both the interesting microphase-separated characteristics of BCPs and the excellent optoelectronic properties of conjugated polymers ...
Juan Peng, Yanchun Han
doaj   +1 more source

Light‐Activated Conjugated Polymers for Antibacterial Photodynamic and Photothermal Therapy

open access: yesAdvanced NanoBiomed Research, 2021
With the growing crisis of the availability of effective antimicrobial treatments, the use of phototherapy has gained increasing interest as an alternative to traditional antibiotic therapy.
Thais Fedatto Abelha   +1 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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