Results 131 to 140 of about 1,208,196 (340)
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Alternant Conjugate Systems. IV. Ultraviolet Spectroscopic Properties and Photoisomerization of Geometrical Isomers ofp-Distyrylbenzenes,p,p′-Distyrylstilbenes and Related Compounds [PDF]
, 1962 Soichi Misumi +2 more
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Stereographically conjugate differential systems
, 2015 Topological bases of behaviour of trajectories for autonomous differential systems of the second order on sphere are stated. Stereographic atlas of trajectories is constructed. Differential connections between trajectories of stereographically conjugate differential systems are established.
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Methods of conjugate gradients for solving linear systems
, 1952 Magnus R. Hestenes, Eduard Stiefel
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Alternant Conjugate Systems. II. Syntheses of Stereoisomericp-Distyrylbenzenes and Related Compounds [PDF]
, 1961 Soichi Misumi +3 more
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2014 In this paper we present the results of some experiments in which substrates representing various unsaturated and aromatic systems were tested in reduction reactions with Ni-Al alloy in aqueous NaOH and we highlight the relationships between the ...
Mirela Suceveanu +3 more
doaj
The conjugation system of staphylococcus aureus
, 1986 A conjugation system in Staphylococcus aureus has been investigated and shown to be determined, at least in part, by genes carried on plasmids. Conjugation required cell-to-cell contact but not calcium ions. The frequency of conjugation depended on the recipient used and on the incubation conditions.
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