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Aromatic stability of heterocyclic conjugated systems [PDF]
Journal of the American Chemical Society, 1985 The graph-theoretical approach for calculation of the aromatic stability of conjugated polycyclic hydrocarbons is extended here to polycyclic systems having a single heteroatom. Advantages of this algebraic approach, which yields expressions for the molecular resonance energies, are discussed.In particular, the relative stabilities of positional ...
Nenad Trinajstić +3 more
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siRNA Conjugate Delivery Systems
Bioconjugate Chemistry, 2008Small interfering RNA (siRNA) has been chemically conjugated to a variety of bioactive molecules, lipids, polymers, peptides, and inorganic nanostructured materials to enhance their pharmacokinetic behavior, cellular uptake, target specificity, and safety. To efficiently deliver siRNAs to the target cells and tissues, many different siRNA bioconjugates
Jeong, JH Jeong, Ji Hoon +3 more
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The Ubiquitin-Conjugation System
Annual Review of Genetics, 1992The ubiquitin/proteasome system is believed to be the major nonlysosomal proteolytic system of eukaryotic cells. It is present in the cytosol and the nucleus but apparently absent from the lumen of membrane-enclosed organelles, i. e., the endoplasmic reticulum, the Golgi and vesicular system, mitochondria, chloroplasts, and peroxisomes (for reviews see
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The Journal of Biochemistry, 2005
ISG15 is a ubiquitin-like protein that is upregulated on treatment with interferon. ISG15 is considered to be covalently conjugated to cellular proteins through a sequential reaction similar to that of the ubiquitin conjugation system consisting of E1/E2/E3 enzymes: UBE1L and UbcH8 have been reported to function as E1 and E2 enzymes, respectively, for ...
Tomoharu Takeuchi +4 more
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ISG15 is a ubiquitin-like protein that is upregulated on treatment with interferon. ISG15 is considered to be covalently conjugated to cellular proteins through a sequential reaction similar to that of the ubiquitin conjugation system consisting of E1/E2/E3 enzymes: UBE1L and UbcH8 have been reported to function as E1 and E2 enzymes, respectively, for ...
Tomoharu Takeuchi +4 more
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Effective conjugation length of π-conjugated systems
Chemical Physics Letters, 2004Abstract The optical absorption of ordered and disordered π-conjugated molecules is described on the same microscopic footing. This gives a concise picture of the length dependence of the optical absorption of π-conjugated systems.
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Conjugation and the periodic system of the elements
Russian Chemical Reviews, 1991The knowledge of the characteristics and mechanisms of the interaction of the active centres of complex molecules is of primary importance for the development of theoretical and applied organic chemistry, promotes a more productive utilisation of the enormous amount of experimental data available, facilitates predictions and the search for new routes ...
Konstantin Ya Burshtein, P. P. Shorygin
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