Results 91 to 100 of about 164,481 (302)

Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]

, 2017
Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R, Guardabassi, L, Jana, B, Sigurðardóttir, H H   +3 more
core   +2 more sources

GENETICS OF CHEMICAL INDUCTION OF CONJUGATION IN PARAMECIUM AURELIA [PDF]

Genetics, 1974
ABSTRACT Certain stocks of P. aurelia, syngen 8, could not be induced to conjugate in a solution (KCl + acriflavine + calcium-poor conditions) which was effective in inducing conjugation in other species of Paramecium as well as in other stocks of syngen 8.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Chloramphenicol resistance genes in Salmonella enterica subsp. enterica serovar Typhimurium isolated from human and animal sources in Hungary

Veterinární Medicína, 2005
The presence of the chloramphenicol resistance genes cat, cmlA, flo, and the role of plasmids and class 1 integrons in the spread and persistence of chloramphenicol resistance were investigated on a collection of 40 Salmonella enterica serovar ...
N. Nogrady, I. Gado, P. Zsolt Fekete, J. Paszti   +3 more
doaj   +1 more source

Influence of the absorber dimensions on wavefront shaping based on volumetric optoacoustic feedback [PDF]

, 2015
The recently demonstrated control over light distribution through turbid media based on real-time three-dimensional optoacoustic feedback has offered promising prospects to interferometrically focus light within scattering objects.
Dean-Ben, X. L., Estrada, H., Ozbek, A., Razansky, D.   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Artificial Conjugation in Escherichia coli and Transfer of Penicillinase Plasmid

پزشکی بالینی ابن سینا, 1999
Conjugation is a major mechanism of DNA transfer among bacteria which takes place in both laboratory and natural environment and brings about new characteristics. Extrachromosomal DNA called plasmid are important elements in this exchange.
Mohammad Javad Kajbaf, Mohammad Ali Mashhadizadeh, Heidar Reza Mohtadi   +2 more
doaj  

Cytogerontology since 1881: A reappraisal of August Weismann and a review of modern progress [PDF]

, 1982
Cytogerontology, the science of cellular ageing, originated in 1881 with the prediction by August Weismann that the somatic cells of higher animals have limited division potential.
A Carrel, A Comfort, A Götte, A Weismann, A Weismann, A Weismann, A Weismann, A Weismann, A Weismann, AH Ebeling, AJ Nienhaus, AL Muggleton-Harris, AO Martinez, AR Sheldrake, AR Williamson, B Charlesworth, B Hill, BL Strehler, C Darwin, C Zavala, CB Harley, CB Harley, CH Evans, CJ Epstein, CL Bunn, CM Child, CM Child, CS Minot, CW Daniel, D Harman, D Kram, D Lack, DA Ogden, DE Brash, E Bell, E Metchnikoff, E Stecker, EL Schneider, F Vogel, FM Burnet, GA Sacher, GC Williams, GH Stein, GJ Todaro, GM Martin, GM Martin, GM Martin, GM Martin, GM Martin, GP Bidder, GR Martin, HE Swim, HEM Kay, HJ Curtis, HR Hirsch, HW Woolhouse, I Zs-Nagy, J Bjorksten, J Maynard Smith, J Maynard Smith, J Ponten, J Smith-Sonneborn, JA Witkowski, JBS Haldane, JF Stanley, JR Smith, JR Smith, JR Smith, K Illmensee, K Kontermann, KH Rothfels, L Hayflick, L Hayflick, L Hayflick, L Szilard, LC Cole, LC Stevens, LE Orgel, LE Orgel, MR Rose, P Calow, PB Medawar, PB Medawar, PL Krohn, R Holliday, R Holliday, R Holliday, R Holliday, R Holliday, R Holliday, R Holliday, R Long De, R Pearl, R Rosenberger, RD Guthrie, RG Cutler, RG Cutler, RW Hart, S Linn, SH Vines, SJ Fulder, T Cremer, TBL Kirkwood, TBL Kirkwood, TBL Kirkwood, TBL Kirkwood, TBL Kirkwood, Thomas B. L. Kirkwood, Thomas Cremer, TM Sonneborn, TM Sonneborn, W Topp, WD Hamilton, ZhA Medvedev, ZhA Medvedev   +114 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source