DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Selective elimination of donor bacteria enables global profiling of plasmid gene expression at early stages of conjugation. [PDF]
Wen M +5 more
europepmc +1 more source
Boundary Control for 2 × 2 Elliptic Systems with Conjugation Conditions
Ahlam Hasan Qamlo, G. M. Bahaa
openalex +2 more sources
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Comprehensive analysis of Enterobacteriaceae IncX plasmids reveals robust conjugation regulators PrfaH, H-NS, and conjugation-fitness tradeoff [PDF]
Jun Yang +10 more
openalex +1 more source
Inter‐individual differences in the glycine conjugation of salicylic acid [proceedings] [PDF]
Jonathan Caldwell +2 more
openalex +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Differential gut transmission of IncP plasmid clades involving hypervirulent Klebsiella pneumoniae reveals plasmid-specific ecological adaptation. [PDF]
Yong M +13 more
europepmc +1 more source
Optimization of Protein Therapies by Polymer-Conjugation as an Effective DDS [PDF]
Hiroko Shibata +2 more
openalex +1 more source

