Results 41 to 50 of about 94,616 (343)
Advanced Healthcare Materials, EarlyView.We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin +5 more
wiley +1 more source
Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]
, 2018 Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice +3 more
core +1 more source
3D Printing Strategies for Bioengineering Human Cornea
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan +4 more
wiley +1 more source
Ocular conjunctival microbiome profiling in dry eye disease: A case control pilot study
Indian Journal of Ophthalmology, 2023 Purpose: Keratoconjunctivitis sicca (KCS) or dry eye disease (DED) is a multifactorial disease that results in discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface.
Noopur Gupta +6 more
doaj +1 more source
Longitudinal Analysis of Antibody Responses to Trachoma Antigens Before and After Mass Drug Administration. [PDF]
, 2014 Blinding trachoma, caused by the bacteria Chlamydia trachomatis, is a neglected tropical disease targeted for elimination by 2020. A major component of the elimination strategy is mass drug administration (MDA) with azithromycin.
Dize, Laura +10 more
core +2 more sources
Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation
Advanced Science, EarlyView.A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun +8 more
wiley +1 more source
A Review of Ocular Surface Impression Cytology Along with the Recommended Methodology
Medical Journal of Dr. D.Y. Patil VidyapeethImpression cytology (IC) using specific filter paper is a non-invasive method to study ocular surface diseases. This method has been continuously under modification from its origin. The yield of cells depends on the properties of the filter paper and the
Rekha Chotaliya +3 more
doaj +1 more source
Frontiers in Immunology, 2021 Sjögren syndrome (SS) is an autoimmune condition that targets the salivary and lacrimal glands, with cardinal clinical signs of dry eye (keratoconjunctivitis sicca, KCS) and dry mouth.
Cintia S. de Paiva +7 more
doaj +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
Advanced Science, EarlyView.This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
, 2018 ‘Conjunctiva’ provides the reader with a practical approach to the assessment and management of conjunctival disease. After outlining the relevant anatomy and physiology of this structure, the chapter addresses the key clinical presentations arising from conjunctival disease, notably infective conjunctivitis (including bacterial, viral and chlamydial),
Appukutty Manickam +2 more
openaire +2 more sources