Results 61 to 70 of about 9,409,354 (304)

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Biomarkers in ocular chronic graft versus host disease: tear cytokine- and chemokine-based predictive model. [PDF]

, 2016
Producción CientíficaPurpose: To develop a tear molecule level-based predictive model based on a panel of tear cytokines and their correlation with clinical features in ocular chronic graft versus host disease (cGVHD).
Caballero, Dolores, Calonge Cano, Margarita, Cocho, Lidia, Enríquez de Salamanca y Aladro, Amalia, Fernández Martínez, Itziar, García Vázquez, Carmen, González García, María Jesús, López Corral, Lucía, Martínez, Verónica, Stern, Michael E., Vázquez, Lourdes   +10 more
core   +2 more sources

Systematic Review and Meta-Analysis of the Occurrence of ESKAPE Bacteria Group in Dogs, and the Related Zoonotic Risk in Animal-Assisted Therapy, and in Animal-Assisted Activity in the Health Context [PDF]

, 2020
Animal-assisted interventions are widely implemented in different contexts worldwide. Particularly, animal-assisted therapies and animal-assisted activities are often implemented in hospitals, rehabilitation centers, and other health facilities.
Fioretti, Alessandro, Menna, Lucia Francesca, Sansone, Mario, Santaniello, Antonio   +3 more
core   +1 more source

Development of Teleoperated Robotic System for Remote Intraocular Microsurgery

Advanced Science, EarlyView.
A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu, Zhangkai Lian, Wenben Chen, Yanlin Li, Jiali Liu, Hongli Liang, Rihui Song, Zikai Lin, Mingyuan Li, Yining Huang, Ling Jin, Zheming Zhang, Xiaoyue Wei, Bingqian Liu, Wei Ma, Tao Li, Hang Shao, Wei Liu, Kun Gao, Xin Zhang, Pisong Yan, Ruiyang Li, Ruixin Wang, Xiaohang Wu, Duoru Lin, Xiang Chen, Jinghui Wang, Xingwu Zhong, Mohammad Ali Nasseri, Kai Huang, Haotian Lin   +30 more
wiley   +1 more source

Current findings of genetic alterations and associated targeted therapies of conjunctival melanocytic neoplasms

Taiwan Journal of Ophthalmology
The molecular landscape of numerous human malignancies has been elucidated since the advances in sequencing techniques. However, unlike their cutaneous counterparts, which have a higher incidence and more affected patients as study subjects, conjunctival
Lei-Chi Wang, Chieh-Chih Tsai, Tai-Chi Lin, Narsing A. Rao   +3 more
doaj   +1 more source

A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]

, 2019
Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes, Calonge Cano, Margarita, Fernández Martínez, Itziar, Galindo de la Rosa, Sara, García-Sancho Martín, Francisco Javier, Herreras Cantalapiedra, José María, López Paniagua, Marina, Nieto Miguel, Teresa, Pérez Soto, María Inmaculada, Sánchez García, Ana María de los Ángeles   +9 more
core   +2 more sources

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

Advanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun, Long Zhao, Zhen Shi, Jingting Wang, Shang Yang, Xia Qi, Hengrui Zhang, Ting Wang, Weiyun Shi   +8 more
wiley   +1 more source

Kynurenic Acid Accelerates Healing of Corneal Epithelium In Vitro and In Vivo

Pharmaceuticals, 2021
Kynurenic acid (KYNA) is an endogenous compound with a multidirectional effect. It possesses antiapoptotic, anti-inflammatory, and antioxidative properties that may be beneficial in the treatment of corneal injuries.
Anna Matysik-Woźniak, Waldemar A. Turski, Monika Turska, Roman Paduch, Mirosław Łańcut, Paweł Piwowarczyk, Mirosław Czuczwar, Robert Rejdak   +7 more
doaj   +1 more source

Keratoprostheses for corneal blindness: a review of contemporary devices [PDF]

, 2015
According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases
Avadhanam, Venkata, Liu, Christopher, Smith, Helen   +2 more
core   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source