Clinical findings and management of conjunctival intraepithelial neoplasia
Optometry - Journal of the American Optometric Association, 2011Conjunctival intraepithelial neoplasia (CIN) is the most common tumor of the ocular surface and is a precursor to invasive squamous cell carcinoma. CIN comprises a spectrum of premalignant epithelial neoplasia that usually begins near the limbus and spreads to the cornea.This case report reviews the clinical findings and management of CIN, with a ...
Kathryn D, Nelson, John J, McSoley
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Conjunctival intraepithelial neoplasia in an HIV-positive patient
International Journal of STD and AIDS, 2009We describe the case of a 37-year-old African woman with an asymptomatic lesion on her right conjunctiva; histology of the lesion revealed the presence of conjunctival intraepithelial neoplasia. HIV-positive patients from Africa are at increased risk of developing conjunctival malignancies, and early diagnosis and treatment can prevent serious ...
B, Serisha, R, Shenoy, J, Evans
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Successful Management of Conjunctival Intraepithelial Neoplasia by Interferon α-2b
Japanese Journal of Ophthalmology, 2002Interferon alpha-2b (IFN alpha 2b) was recently shown to be effective as an alternative therapy for conjunctival intraepithelial neoplasia (CIN). Herein, we report our successful management of CIN by the use of IFN alpha 2b.A 73-year-old woman presented with a complaint of irritation due to a tumorous lesion in her left eye.
Akira Kobayashi +2 more
exaly +3 more sources
Expression of p63 in conjunctival intraepithelial neoplasia and squamous cell carcinoma
Graefe's Archive for Clinical and Experimental Ophthalmology, 2005p63 is a homologue of the tumour suppressor gene p53, which is expressed in human basal squamous epithelium. Some investigators maintain that p63 plays a role in the development of squamous epithelium and, despite its homology to p53, it is considered to act as an oncogene.
Claudia Auw-Haedrich, Nicolas Feltgen
exaly +4 more sources
Conjunctival squamous intraepithelial neoplasia and its differential diagnosis
Journal of Clinical Pathology, 2021Conjunctival squamous intraepithelial neoplasia (CSIN) represents the in situ precursor of squamous cell carcinoma. The graded severity of intraepithelial dysplasia is considered a measure of risk for progression to invasive carcinoma. The range of cytoarchitectural changes in CSIN overlaps those of reactive atypia, squamous epithelial papilloma and in
Alexander Reese, Curtis Edward Margo
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Detection, aetiology and management of conjunctival intraepithelial neoplasia
Ophthalmic and Physiological Optics, 2000Summary Conjunctival intraepithelial neoplasia (CIN) are considered to be the third most common ocular tumour and the most common tumour of the ocular surface. Due to their malignant potential, they must be carefully differentially and promptly treated.
A, Jaworski, J S, Wolffsohn, G A, Napper
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Corneal and Conjunctival Intraepithelial Neoplasia
1997A retrospective study identifying 306 patients (326 pathology samples; 59.74% of whom were males) with a corneal and conjunctival intraepithelial neoplasia (CIN) was performed. The neoplasia was conjunctival in 213 (69.6%) and corneal in 94 (30.7%) of the cases studied.
Francisco Barraquer, Luis F. Mejía
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Mitomycin C Therapy for Conjunctival-Corneal Intraepithelial Neoplasia
Cornea, 2002To evaluate the efficacy and safety of topical mitomycin C (MMC) for conjunctival-corneal intraepithelial neoplasia (CCIN).One patient with primary CCIN received seven applications for 3 minutes of mitomycin C 0.02%, for 2 weeks, on alternative days. The size of the CCIN before and after the treatment and ophthalmic mitomycin C related complications ...
Andreas A, Papandroudis +2 more
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Human Papillomavirus Type 18 in Conjunctival Intraepithelial Neoplasia
American Journal of Ophthalmology, 1990Human papillomaviruses are oncogenic viruses that have been found in a variety of epithelial neoplasias. We sought to confirm their presence in conjunctival intraepithelial neoplasia. Five tumors were studied with a polymerase chain-reaction assay designed to detect the E6 region of human papillomavirus types 16 and 18. Human papillomavirus type-16 DNA
S A, Lauer, J S, Malter, J R, Meier
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In vivo confocal microscopy in a patient with recurrent conjunctival intraepithelial neoplasia
Acta Ophthalmologica, 2008CM may be particularly useful in the follow-up of the disease if mild recurrence is suspected. Further studies are necessary to establish methods of correctly diagnosing limbal tumours by CM and for improving the comparison lesions to histological features by CM.
Malandrini, Alex +3 more
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