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The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia [PDF]

open access: yesSouth African Family Practice
Ocular surface squamous neoplasia (OSSN) encompasses a spectrum of conjunctival tumours and, while rare globally, is the most common ocular malignancy in sub-Saharan Africa. Its rising incidence, primarily driven by the human immunodeficiency virus (HIV)
Leendert Dekker   +2 more
doaj   +4 more sources

Pigmented versus nonpigmented ocular surface squamous neoplasia: A comparative study of 424 tumors [PDF]

open access: yesTaiwan Journal of Ophthalmology
PURPOSE: The purpose of this study was to compare the clinical features, management, and outcomes of patients with pigmented ocular surface squamous neoplasia (p-OSSN) versus nonpigmented OSSN (np-OSSN).
Kavya Madhuri Bejjanki   +3 more
doaj   +2 more sources

Observation of angiographic dye leakage in ocular surface squamous neoplasia [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: The clinical diagnosis of ocular surface squamous neoplasia is challenging, mostly requiring excisional biopsy. Human tumor angiogenesis is characterized by abnormal vessel architecture and transvascular hyperpermeability.
Christoph Palme   +5 more
doaj   +4 more sources

Establishment of a nomogram model to predict malignant risk in patients with ocular surface squamous neoplasia and ocular surface squamous epithelial tumors [PDF]

open access: yesFrontiers in Oncology
ObjectiveTo develop and internally validate a nomogram to predict the probability that a clinically suspected ocular surface squamous epithelial tumor is histopathologically malignant.MethodsThis retrospective study included 92 patients with ocular ...
Xie Fang   +53 more
doaj   +2 more sources

Management Issues in Conjunctival Tumours: Ocular Surface Squamous Neoplasia

open access: yesOphthalmology and Therapy, 2019
Ocular surface squamous neoplasia is the most common tumour of the ocular surface. It is a spectrum of disease from intraepithelial dysplasia to invasive squamous cell carcinoma.
Victoria M. L. Cohen   +1 more
doaj   +3 more sources

Immunohistochemical and mutational status of telomerase reverse transcriptase in conjunctival squamous cell carcinoma

open access: yesIndian Journal of Ophthalmology, 2022
Purpose: Mutations in human telomerase reverse transcriptase (TERT) are associated with increased telomerase activity in cutaneous melanomas. Conjunctival squamous cell carcinoma, also referred to as ocular surface squamous cell carcinoma, is cancer on ...
Perumal Jayaraj   +7 more
doaj   +1 more source

Ocular surface squamous neoplasia: Population demographics, pathogenesis and risk factors

open access: yesAfrican Vision and Eye Health, 2020
Background: Ocular surface squamous neoplasia (OSSN) is a unifying term used to describe conjunctival intra-epithelial neoplasia, squamous cell carcinoma in situ and invasive squamous cell carcinoma.
Roland Hollhumer   +2 more
doaj   +1 more source

Conjunctival Ocular Surface Squamous Neoplasia with Spheroidal Degeneration: A Rare Case of UV-B Associated Ocular Neoplasia and Keratopathy [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Ocular Surface Squamous Neoplasia (OSSN) is an umbrella term that includes a broad spectrum of conjunctival and corneal malignancies, ranging from mild epithelial dysplasia to invasive squamous cell carcinoma.
Gunvanti Rathod   +4 more
doaj   +1 more source

Intraocular Spread of Ocular Surface Squamous Neoplasia Presenting as a Postoperative Anterior Chamber Opacity after Excisional Biopsy

open access: yesCase Reports in Ophthalmology, 2023
We describe a rare case of ocular surface squamous neoplasia (OSSN) with intraocular spread after excisional biopsy which presented as a postoperative anterior chamber (A/C) opacity, initially thought to be a hypopyon.
Sarah Pike   +5 more
doaj   +1 more source

Ocular Surface Squamous Neoplasia

open access: yesDelhi Journal of Ophthalmology, 2012
Ocular surface squamous neoplasia (OSSN) are important because they mimic many common indolent lesions like pterygium and have a potential for causing ocular and systemic morbidity and mortality.
Sandeep Gupta   +3 more
doaj   +1 more source

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