Results 1 to 10 of about 4,998,430 (314)
Ophthalmology and Therapy, 2023 Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs and symptoms. However, patients with DED have very limited treatment options for management of both signs and symptoms of ...
Michela Montecchi-Palmer +5 more
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Safety and Efficacy of Corneal Cross-Linking in Patients Affected by Keratoconus: Long-Term Results
Medical Sciences, 2023 The present study evaluated the effectiveness and safety of corneal collagen cross-linking (CXL). A total of 886 eyes with progressive keratoconus were enrolled in a retrospective cohort study in a tertiary care university hospital.
Karl Anders Knutsson +8 more
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Topical fosaprepitant for the treatment of ocular pain and inflammation
American Journal of Ophthalmology Case Reports, 2023 Purpose: To assess whether topical administration of fosaprepitant improves intractable chronic ocular pain and inflammation. Methods: We report three clinical cases of female patients with drug-resistant ocular pain associated with inflammatory diseases
Giuseppe Suanno +4 more
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IL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRα Mutant Mouse
Frontiers in Medicine, 2022 PurposeTo investigate IL-17 related mechanisms for developing dry eye disease in the Pinkie mouse strain with a loss of function RXRα mutation.MethodsMeasures of dry eye disease were assessed in the cornea and conjunctiva.
Jehan Alam +9 more
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Advances in clinical examination of lacrimal gland
Frontiers in Medicine, 2023 In humans, the lacrimal gland is located in the socket of the frontal bone above the outer orbital area. As an essential part of the eye surface, the gland is fixed to the orbital periosteum by connective tissue.
Yuan Lin +20 more
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Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges
Pharmaceutics, 2021 Advanced therapy medicinal products (ATMPs) are a novel class of medicines with enormous potential to improve treatments for a wide range of diseases, including those affecting eye structures [...]
Yolanda Diebold, Laura García-Posadas
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A stepping stone in treating dendritic keratitis
American Journal of Ophthalmology Case Reports, 2017 Purpose: To report the outcome of self-retained amniotic membrane after debridement in recurrent dendritic keratitis. Observations: A 70-year-old female with a recurrent dendritic corneal ulcer received debridement followed by placement of self-retained ...
Hosam Sheha, MD, PhD +3 more
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Gut-derived butyrate suppresses ocular surface inflammation
Scientific Reports, 2022 Dry eye is a common ocular inflammatory disorder characterized by tear film instability and reduced tear production. There is increasing evidence that homeostasis of the ocular surface is impacted by the intestinal microbiome.
Laura Schaefer +6 more
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Is the Conjunctiva a Potential Target for Advanced Therapy Medicinal Products?
Pharmaceutics, 2021 The conjunctiva is a complex ocular tissue that provides mechanical, sensory, and immune protection for the ocular surface. It is affected by many diseases through different pathological mechanisms.
Yolanda Diebold, Laura García-Posadas
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Ocular surface evaluation in eyes with chronic glaucoma on long term topical antiglaucoma therapy [PDF]
International Journal of Ophthalmology, 2017 AIM: To evaluate ocular surface changes and its correlation with the central corneal subbasal nerve fibre layer in chronic glaucoma patients. METHODS: A prospective comparative study of ocular surface evaluation was performed in 50 eyes of 25 patients ...
Manu Saini +5 more
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