Results 1 to 10 of about 134,436 (168)

Establishment of a nomogram model to predict malignant risk in patients with ocular surface squamous neoplasia and ocular surface squamous epithelial tumors [PDF]

open access: yesFrontiers in Oncology
ObjectiveTo develop and internally validate a nomogram to predict the probability that a clinically suspected ocular surface squamous epithelial tumor is histopathologically malignant.MethodsThis retrospective study included 92 patients with ocular ...
Xie Fang   +53 more
doaj   +2 more sources

Tribology and the Ocular Surface [PDF]

open access: yesClinical Ophthalmology, 2022
Tribology is known as the science of friction, lubrication and the determination of what occurs when two surfaces slide against one another. The required partners in this science are a minimum of two surfaces and relative motion. Tribology could be a key factor in dissecting the issues that surround and confound dry eye in patients as well as contact ...
Chris W Lievens, Elyse Rayborn
openaire   +3 more sources

Possible Strategies to Mitigate Placebo or Vehicle Response in Dry Eye Disease Trials: A Narrative Review

open access: yesOphthalmology and Therapy, 2023
Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs and symptoms. However, patients with DED have very limited treatment options for management of both signs and symptoms of ...
Michela Montecchi-Palmer   +5 more
doaj   +1 more source

Safety and Efficacy of Corneal Cross-Linking in Patients Affected by Keratoconus: Long-Term Results

open access: yesMedical Sciences, 2023
The present study evaluated the effectiveness and safety of corneal collagen cross-linking (CXL). A total of 886 eyes with progressive keratoconus were enrolled in a retrospective cohort study in a tertiary care university hospital.
Karl Anders Knutsson   +8 more
doaj   +1 more source

Ocular surface tumors

open access: yesOman Journal of Ophthalmology, 2009
Tumors of the conjunctiva and cornea comprise a large and varied spectrum of conditions. These tumors are grouped into two major categories of congenital and acquired lesions. The acquired lesions are further subdivided based on origin of the mass into surface epithelial, mucoepidermoid, melanocytic, vascular, fibrous, neural, histiocytic, myxoid ...
Meghana Anika Varde, Jyotirmay Biswas
openaire   +6 more sources

Assessing the ocular surface microbiome in severe ocular surface diseases [PDF]

open access: yesThe Ocular Surface, 2020
There is growing evidence for a critical role of the microbiome in ocular health and disease. We performed a prospective, observational study to characterize the ocular surface microbiome (OSM) in four chronic ocular surface diseases (OSDs) and healthy controls.Sterile swabs were used to collect samples from each eye of 39 patients (78 eyes).
Michael J. Zilliox   +6 more
openaire   +2 more sources

Topical fosaprepitant for the treatment of ocular pain and inflammation

open access: yesAmerican Journal of Ophthalmology Case Reports, 2023
Purpose: To assess whether topical administration of fosaprepitant improves intractable chronic ocular pain and inflammation. Methods: We report three clinical cases of female patients with drug-resistant ocular pain associated with inflammatory diseases
Giuseppe Suanno   +4 more
doaj   +1 more source

IL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRα Mutant Mouse

open access: yesFrontiers in Medicine, 2022
PurposeTo investigate IL-17 related mechanisms for developing dry eye disease in the Pinkie mouse strain with a loss of function RXRα mutation.MethodsMeasures of dry eye disease were assessed in the cornea and conjunctiva.
Jehan Alam   +9 more
doaj   +1 more source

Advances in clinical examination of lacrimal gland

open access: yesFrontiers in Medicine, 2023
In humans, the lacrimal gland is located in the socket of the frontal bone above the outer orbital area. As an essential part of the eye surface, the gland is fixed to the orbital periosteum by connective tissue.
Yuan Lin   +20 more
doaj   +1 more source

Impact of Microplastics on the Ocular Surface

open access: yesInternational Journal of Molecular Sciences, 2023
Plastics are synthetic materials made from organic polymers that are ubiquitous in daily living and are especially important in the healthcare setting. However, recent advances have revealed the pervasive nature of microplastics, which are formed by degradation of existing plastic products.
Duoduo Wu   +17 more
openaire   +4 more sources

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