Results 11 to 20 of about 134,535 (267)
Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges
Pharmaceutics, 2021 Advanced therapy medicinal products (ATMPs) are a novel class of medicines with enormous potential to improve treatments for a wide range of diseases, including those affecting eye structures [...]
Yolanda Diebold, Laura García-Posadas
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A stepping stone in treating dendritic keratitis
American Journal of Ophthalmology Case Reports, 2017 Purpose: To report the outcome of self-retained amniotic membrane after debridement in recurrent dendritic keratitis. Observations: A 70-year-old female with a recurrent dendritic corneal ulcer received debridement followed by placement of self-retained ...
Hosam Sheha, MD, PhD +3 more
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Gut-derived butyrate suppresses ocular surface inflammation
Scientific Reports, 2022 Dry eye is a common ocular inflammatory disorder characterized by tear film instability and reduced tear production. There is increasing evidence that homeostasis of the ocular surface is impacted by the intestinal microbiome.
Laura Schaefer +6 more
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Is the Conjunctiva a Potential Target for Advanced Therapy Medicinal Products?
Pharmaceutics, 2021 The conjunctiva is a complex ocular tissue that provides mechanical, sensory, and immune protection for the ocular surface. It is affected by many diseases through different pathological mechanisms.
Yolanda Diebold, Laura García-Posadas
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Ocular surface evaluation in eyes with chronic glaucoma on long term topical antiglaucoma therapy [PDF]
International Journal of Ophthalmology, 2017 AIM: To evaluate ocular surface changes and its correlation with the central corneal subbasal nerve fibre layer in chronic glaucoma patients. METHODS: A prospective comparative study of ocular surface evaluation was performed in 50 eyes of 25 patients ...
Manu Saini +5 more
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Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells
Eye and Vision, 2017 Background Gram-positive bacteria stimulate Toll-like receptor (TLR) 2 and then activate the pro-inflammatory nuclear factor-kappa B (NF-κB) pathway.
Aihua Hou, Min Qi Tin, Louis Tong
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Frontiers in Medicine, 2021 Purpose: To conduct a multi-center analysis and assess the economic burden due to dry eye disease (DED) in China.Design: A retrospective and cross-sectional study.Methods: Patients (n = 598) with diagnosed DED were recruited from 3 eye centers (in ...
Wanju Yang +29 more
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Advanced Therapy Medicinal Products for the Eye: Definitions and Regulatory Framework
Pharmaceutics, 2021 Advanced therapy medicinal products (ATMPs) are a group of innovative and complex biological products for human use that comprises somatic cell therapy medicinal products, tissue engineered products, gene therapy medicinal products, and the so-called ...
Marina López-Paniagua +5 more
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A novel pupilloplasty in crescent-shaped suturing pattern for coloboma and traumatic iris defects
BMC Ophthalmology, 2023 Objective Purpose To observe the safety and effect of the C-pupilloplasty for the treatment of iris coloboma and traumatic iris defects. Methods A total of 21 cases (21 eyes) with iris coloboma or traumatic iris defects who underwent C-pupilloplasty (a ...
Xiaoming Yao +8 more
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Applied Sciences, 2021 Ocular graft-versus-host disease (oGVHD) is a manifestation of chronic GVHD, frequently occurring in patients after allogeneic hematopoietic stem cell transplant (HSCT).
Carmen Ciavarella +6 more
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