Results 11 to 20 of about 259,165 (312)

Is the Conjunctiva a Potential Target for Advanced Therapy Medicinal Products?

Pharmaceutics, 2021
The conjunctiva is a complex ocular tissue that provides mechanical, sensory, and immune protection for the ocular surface. It is affected by many diseases through different pathological mechanisms.
Yolanda Diebold, Laura García-Posadas
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A stepping stone in treating dendritic keratitis

American Journal of Ophthalmology Case Reports, 2017
Purpose: To report the outcome of self-retained amniotic membrane after debridement in recurrent dendritic keratitis. Observations: A 70-year-old female with a recurrent dendritic corneal ulcer received debridement followed by placement of self-retained ...
Hosam Sheha, MD, PhD, Sean Tighe, MSc, Anny M.S. Cheng, MD, Scheffer C.G. Tseng, MD, PhD   +3 more
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Gut-derived butyrate suppresses ocular surface inflammation

Scientific Reports, 2022
Dry eye is a common ocular inflammatory disorder characterized by tear film instability and reduced tear production. There is increasing evidence that homeostasis of the ocular surface is impacted by the intestinal microbiome.
Laura Schaefer, Humberto Hernandez, Rosalind A. Coats, Zhiyuan Yu, Stephen C. Pflugfelder, Robert A. Britton, Cintia de Paiva   +6 more
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Impacto da poluição ambiental na superfície ocular de pacientes com síndrome de Sjögren [PDF]

, 2018
Purpose: To evaluate the effect of air pollution on the ocular surface of patients with Sjögren's syndrome. Methods: We investigated the ocular surfaces of thirty patients with Sjögren's syndrome and thirty healthy volunteers (control group) living in ...
Berra, Alejandro, Berra, Fabio Martín, Galperín, Gustavo Javier, Mandaradoni, Mariana, Marquez, Maria Isabel, Tau, Julia   +5 more
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Ocular surface evaluation in eyes with chronic glaucoma on long term topical antiglaucoma therapy [PDF]

International Journal of Ophthalmology, 2017
AIM: To evaluate ocular surface changes and its correlation with the central corneal subbasal nerve fibre layer in chronic glaucoma patients. METHODS: A prospective comparative study of ocular surface evaluation was performed in 50 eyes of 25 patients ...
Manu Saini, Murugesan Vanathi, Tanuj Dada, Tushar Agarwal, Rebika Dhiman, Sudarshan Khokhar   +5 more
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Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study

Frontiers in Medicine, 2021
Purpose: To conduct a multi-center analysis and assess the economic burden due to dry eye disease (DED) in China.Design: A retrospective and cross-sectional study.Methods: Patients (n = 598) with diagnosed DED were recruited from 3 eye centers (in ...
Wanju Yang, Yanzhu Luo, Yanzhu Luo, Yanzhu Luo, Shangcao Wu, Xiaoxia Niu, Yanshuang Yan, Chen Qiao, Chen Qiao, Wei Ming, Wei Ming, Ying Zhang, Haoyu Wang, Haoyu Wang, Dan Chen, Dan Chen, Mengying Qi, Mengying Qi, Lan Ke, Lan Ke, Ying Wang, Ying Wang, Liping Li, Liping Li, Shaowei Li, Qingyan Zeng, Qingyan Zeng, Qingyan Zeng, Qingyan Zeng, Qingyan Zeng   +29 more
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Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells

Eye and Vision, 2017
Background Gram-positive bacteria stimulate Toll-like receptor (TLR) 2 and then activate the pro-inflammatory nuclear factor-kappa B (NF-κB) pathway.
Aihua Hou, Min Qi Tin, Louis Tong
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Advanced Therapy Medicinal Products for the Eye: Definitions and Regulatory Framework

Pharmaceutics, 2021
Advanced therapy medicinal products (ATMPs) are a group of innovative and complex biological products for human use that comprises somatic cell therapy medicinal products, tissue engineered products, gene therapy medicinal products, and the so-called ...
Marina López-Paniagua, Ana de la Mata, Sara Galindo, Francisco Blázquez, Margarita Calonge, Teresa Nieto-Miguel   +5 more
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Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz, Alio, Ambrosio, Djalilian, Dogru, Li, Nebbioso, Nebbioso, Patel, Rajan, Solomon, Suzuki, Toda, Wilson, Zhu   +14 more
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Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine [PDF]

, 2016
In the field of predictive, preventive and personalised medicine, researchers are keen to identify novel and reliable ways to predict and diagnose disease, as well as to monitor patient response to therapeutic agents.
A Acera, A Alonso, A Enríquez-de-Salamanca, A Enríquez-de-Salamanca, A Enríquez-de-Salamanca, A Ghaffariyeh, A Jemal, A Lambiase, A Lebrecht, A Lebrecht, A Leonardi, A Leonardi, A Leonardi, A Leonardi, A Leonardi, A Leonardi, A López-Miguel, A López-Miguel, A Peral, A Rentka, A Rentka, A Riemens, A Satici, A Solomon, AM Lemp, AP Smith, B Houser, B Li, B Ujhelyi, Biomarkers Definitions Working Group, BL Kolozsvári, C Aass, C Costagliola, C Galbis-Estrada, C Galbis-Estrada, C Joffre, C Lebrun, C Salvisberg, C Symeonidis, C Tamer, CG Begley, CM Cheung, CM Tanner, CS Paiva De, D Böhm, D Devos, D Huang, D Karamichos, D Pieragostino, D Pieragostino, D Pieragostino, DK Sen, E Csősz, E Nivenius, E Papavasileiou, E Toker, E Uchio, EA Mahmoud, EB Cook, EB Cook, EM Messmer, FH Grus, G Danaei, G Geerling, G Grech, G Martino, GU Kallarackal, GW Ousler, H Lam, H Link, HG Boersma, HJ Kim, HR Taylor, HV Nema, IA Mackie, J Jin, J Shoji, J Shoji, J Soria, J Tauber, J You, J You, JB Roedl, JC Pong, JC Pong, JE Moore, JF Huang, JG Ladas, JM Holopainen, JM Holopainen, JW Jung, K Cai, KC Yoon, KC Yoon, KK Nichols, KR VanDerMeid, KS Na, KS Park, L Cocho, L Tong, L Tong, L Zhou, L Zhou, L Zhou, M Börger, M Calonge, M Mavra, M Mrugacz, M Mrugacz, M Mrugacz, M Sacchetti, M Schicht, M Tesón, M Tishler, M Zandbelt, MA Lemp, MA Mowafy, MB Abelson, MB Goren, ME Stern, MH Jagasia, ML Massingale, N Boehm, N Boehm, N Dong, N Matheis, N Thun Und Hohenstein-Blaul von, N Tomosugi, O Golubnitschaja, O Golubnitschaja, OD Schein, P Aragona, P Argüeso, P Chhadva, P Versura, PG Montan, PK Coyle, PK Coyle, PS Goedegebuure, Q Guo, R Ihnatko, R Sack, R Shetty, R Sorkhabi, R Tailor, S Chotikavanich, S Darougar, S D’Souza, S Gutman, S Hagan, S Hagan, S Rusnak, S Vujosevic, S Yavuz, SA Lim, SC Pflugfelder, SF Hamm-Alvarez, SG Wu, SM Lam, SM Lam, SS Çomoğlu, SV Aluru, SY Lee, T Göncü, T Matsumura, T Nguyen-Khuong, T Peto, T Sakimoto, T Skwor, TH Wakamatsu, V Evans, VA Smith, VV Kapetanakis, W Choi, W Choi, W Liu, X Tan, Y Ogawa, Y Ohashi, YC Tham, YS Rabinowitz, Z Lei, Z Torok, Z Torok   +183 more
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