Results 41 to 50 of about 4,998,430 (314)

Dynamics of ocular surface topography

, 2007
PURPOSE: To investigate fluctuations in the ocular surface, we used high-speed videokeratoscopy (50 Hz) to measure the dynamics of the ocular surface topography.
D R Iskander, Zhu, Mingxia, M Zhu, Iskander, D. Robert, M J Collins, Collins, Michael J.   +5 more
core   +1 more source

Conjunctival T Cell Profile in Allogeneic Hematopoietic Stem Cell Transplant Patients after Instilling Topical Cyclosporine-A 0.1% Cationic Emulsion

Ophthalmology and Therapy, 2023
Introduction To profile conjunctival T cell populations in allogeneic hematopoietic stem cell transplant (HSCT) patients after instillation of daily topical cyclosporine-A (CsA) 0.1% cationic emulsion (Ikervis), and to evaluate patients’ tolerance to ...
Louis Tong, Elizabeth Wen Ling Lim, Sharon Wan Jie Yeo, Aihua Hou, Yeh Ching Linn, Aloysius Ho, Hein Than, Jeffrey Kim Siang Quek, William Ying Khee Hwang, Francesca Lorraine Wei Inng Lim, Li Lim   +10 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Review and analysis of grading scales for ocular surface staining

, 2019
Vital dye staining has been used for over a century to assess the severity of ocular surface disease. However, despite common usage, a universally accepted “gold standard” grading scale does not exist for corneal and conjunctival staining, which can ...
Simpson, T, Begley, Carolyn G, Caffery, B, Chalmers, R, Situ, Ping, Nelson, J D   +5 more
core   +1 more source

Investigating the Ocular Surface Microbiome: What Can It Tell Us? [PDF]

, 2023
While pathogens of the eye have been studied for a very long time, the existence of resident microbes on the surface of healthy eyes has gained interest only recently. It appears that commensal microbes are a normal feature of the healthy eye, whose role
Zysset-Burri, Denise C, Herzog, Elio L, Morandi, Sophia C, Peter, Virginie G, Zinkernagel, Martin S, Virginie G Peter, Sophia C Morandi, Martin S Zinkernagel, Denise C Zysset-Burri, Elio L Herzog   +9 more
core   +2 more sources

Efficacy of epidermal growth factor in suppressing inflammation and proliferation in pterygial fibroblasts through interactions with microenvironmental M1 macrophages

Scientific Reports
The protein epidermal growth factor (EGF), which plays a crucial role in promoting cell proliferation and survival, has recently demonstrated potential in reducing inflammation.
Soo Jin Lee, Ahra Koh, Seung Hyeun Lee, Kyoung Woo Kim   +3 more
doaj   +1 more source

Effects of Sodium Hyaluronate Eye Drops With or Without Preservatives on Ocular Surface Bacterial Microbiota

Frontiers in Medicine, 2022
PurposeThis study aimed to determine the composition and diversity of bacterial communities on the ocular surface before and after the intervention with sodium hyaluronate eye drops (with or without preservatives) using 16S rRNA gene amplicon sequencing ...
Yanlin Zhong, Yanlin Zhong, Xie Fang, Xie Fang, Xuemei Wang, Xuemei Wang, Yu-An Lin, Yu-An Lin, Huping Wu, Huping Wu, Cheng Li, Cheng Li   +11 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Is dry eye disease the same in young and old patients? A narrative review of the literature

BMC Ophthalmology, 2022
Advanced age is one of the most evident risk factors for dry eye disease (DED), with male/female sex, chronic drug consumption, and prolonged device use.
Stefano Barabino
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source