Results 41 to 50 of about 134,535 (267)
Enrichment protocols for human conjunctival extracellular vesicles and their characterization
Scientific ReportsThe understanding of the role played by extracellular vesicles (EVs) in different tissues has improved significantly in the last years, but remains limited concerning the conjunctiva, a complex eye tissue whose role is pivotal for corneal protection ...
Ismael Romero-Castillo +3 more
doaj +1 more source
Ocular Surface Infection and Antimicrobials
Antibiotics, 2022 Infection of the ocular surface can have devastating consequences if not appropriately treated with antimicrobials at an early stage [...]
Dutta, D, Stapleton, F, Willcox, M
openaire +4 more sources
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Cooperative role of MDSCs and Tregs in alum-induced alloimmune tolerance in corneal transplantation
Scientific ReportsAlum, a widely used adjuvant, has recently been recognized for its capacity to modulate immune responses beyond classical activation. In this study, we investigated whether alum-induced expansion of myeloid-derived suppressor cells (MDSCs) and their ...
Lifang Li +6 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Non-traumatic bilateral corneal flap dislocation 20 years after LASIK
BMC OphthalmologyBackgroud This report describes a case of late non-traumatic dislocation of bilateral corneal flaps, occurring 20 years after LASIK surgery. Case presentation A 52-year-old woman underwent LASIK surgery on both eyes 20 years ago.
Dakun Ren +3 more
doaj +1 more source
Ageing and ocular surface immunity [PDF]
British Journal of Ophthalmology, 2016 The prevalence of ocular surface immunopathologies is enhanced in the elderly. This increased prevalence has been attributed to age-related dysregulation of innate and adaptive immune system responses. Age-related changes in ocular surface immunity have similar and distinct characteristics to those changes seen in other mucosal tissues.
Alireza, Mashaghi +3 more
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Journal of Ophthalmology, 2018 Purpose. To report degeneration of subbasal corneal nerves and the subsequent neuroregeneration in a case of acute ultraviolet (UV) keratitis, treated with autologous serum eye drops. Methods. Case report. Results.
Farshad Abedi, Pedram Hamrah
doaj +1 more source