Results 31 to 40 of about 4,998,430 (314)

Topical glaucoma medications:Clinical implications for the ocular surface [PDF]

, 2022
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility of the compound.
Miriam Kolko, Utheim, Tor P.,, Neil Lagali, Vehof, Jelle,, Adil, Muhammed Yasin, Fineide, Fredrik,, Arita, Reiko, Arita, Reiko,, Fineide, Fredrik, Muhammed Yasin Adil, Utheim, Tor Paaske, Lagali, Neil, Tor P. Utheim, Lagali, Neil Satish, Jelle Vehof, Utheim, Tor P., Vehof, Jelle, Fredrik Fineide, Kolko, Miriam,, Reiko Arita, Lagali, Neil,, Kolko, Miriam, Adil, Muhammed Yasin,   +22 more
core   +1 more source

The clinicopathological analysis of ocular and orbit tumors in southeast of China

Frontiers in Oncology, 2023
PurposeThe purpose of this study is to describe the clinicopathologic characteristics of ocular surface and orbit tumors in the Southeast of China and explore the method to differentiate the benign and malignant masses.Materials and methods3468 patients ...
Yuan Lin, Yuan Lin, Xiaodong Liu, Xiaodong Liu, Yujie Zhang, Yujie Zhang, Zhiwen Xie, Zhiwen Xie, Xie Fang, Xie Fang, Ke Shi, Ke Shi, Yanlin Zhong, Yanlin Zhong, Shengqi Su, Shengqi Su, Shengqi Su, Minqing Cai, Minqing Cai, Huping Wu, Huping Wu, Shangkun Ou, Shangkun Ou   +22 more
doaj   +1 more source

The use of high resolution optical coherence tomography (HR-OCT) in the diagnosis of ocular surface masqueraders

, 2022
Ocular surface masqueraders encompass any ocular surface lesion masquerading as another ocular surface lesion. High resolution optical coherence tomography (HR-OCT) has emerged as an adjunctive tool to clinical acumen. This study's purpose is to evaluate
Sander, Dubovy L, Theotoka, Despoina, Sripawadkul, Wathanee, Galor, Anat, Khzam, Rayan Abou, Tang, Vincent, Karp, Carol L, Wall, Sarah, Vincent Tang, Despoina Theotoka, Carol L. Karp, Wathanee Sripawadkul, Dubovy L. Sander, Anat Galor, Sarah Wall, Rayan Abou Khzam   +15 more
core   +1 more source

Impact of blinking on ocular surface and tear film parameters

, 2018
PURPOSE:To investigate the influence of blinking on tear film parameters, ocular surface characteristics, and dry eye symptomology. METHODS:A total of 154 participants were recruited in an age, gender and ethnicity-matched cross-sectional study, of which
Jung Min Lee, Maria Markoulli, Tien, Leslie, Kim, Dabin, Markoulli, Maria, Alicia Han, Han, Alicia, Lee, Jung Min, Jennifer P. Craig, Michael T.M. Wang, Dabin Kim, Leslie Tien, Craig, Jennifer P, Wang, Michael TM   +13 more
core   +1 more source

Trehalose for Ocular Surface Health [PDF]

Biomolecules, 2020
Trehalose is a natural disaccharide synthesized in various life forms, but not found in vertebrates. An increasing body of evidence demonstrates exceptional bioprotective characteristics of trehalose. This review discusses the scientific findings on potential functions of trehalose in oxidative stress, protein clearance, and inflammation, with an ...
Jarmo Laihia, Kai Kaarniranta
openaire   +3 more sources

Understanding chronic ocular surface pain: An unmet need for targeted drug therapy

, 2022
Chronic ocular surface pain (COSP) may be defined as a feeling of pain, perceived as originating from the ocular surface, that persists for >3 months. COSP is a complex multifactorial condition associated with several risk factors that may significantly ...
Attal, Nadine, Labetoulle, Marc, Galor, Anat, Hamrah, Pedram, Haque, Sameena   +4 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

TFOS: Unique challenges and unmet needs for the management of ocular surface diseases throughout the world

, 2021
The mission of the Tear Film & Ocular Surface Society (TFOS) is to advance the research, literacy, and educational aspects of the scientific field of the tear film and ocular surface.
Margolis T., Vehof J., Mechleb N., Sullivan A. G., Versura P., Abad J. C., Shaheen M. S., Sotozono C., Barabino S., Alves M., Said R. B., Kinoshita S., Navas A., Erickson S., Nsubuga N., Jarade E. F., Stapleton F., Iyer G., Lazreg S., Kobia-Acquah E., Sullivan D. A., Eid M., Gomes J. A. P., Craig J. P., Farrant S., Heydenrych L.   +25 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source