Results 21 to 30 of about 134,535 (267)

The Dry Eye Disease Activity Log Study

open access: yesThe Scientific World Journal, 2012
Prolonged visually stressful activities aggravate dry eye disease (DED). The duration spent on such activities and their relationship with DED clinical features were investigated.
Jayant V. Iyer, Sze-Yee Lee, Louis Tong
doaj   +1 more source

Coping with dry eyes: a qualitative approach

open access: yesBMC Ophthalmology, 2018
Background Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with ...
Sharon Yeo, Louis Tong
doaj   +1 more source

Epidemiology of Corneal Neovascularization and Its Impact on Visual Acuity and Sensitivity: A 14-Year Retrospective Study

open access: yesFrontiers in Medicine, 2021
Purpose: To quantify the severity and location of corneal neovascularization (cNV) and its impact on the visual acuity and corneal sensitivity in a cohort of the patients referred to a specialist cornea clinic and also to describe the etiology of cNV in ...
Romina Mayra Lasagni Vitar   +6 more
doaj   +1 more source

Antioxidant Defenses in the ocular surface [PDF]

open access: yesThe Ocular Surface, 2009
The human eye is subjected constantly to oxidative stress due to daily exposure to sunlight, high metabolic activities, and oxygen tension. Reactive oxygen species generated from environmental insults and pathological conditions render the human eye particularly vulnerable to oxidative damage.
Ying, Chen   +2 more
openaire   +2 more sources

The clinicopathological analysis of ocular and orbit tumors in southeast of China

open access: yesFrontiers in Oncology, 2023
PurposeThe purpose of this study is to describe the clinicopathologic characteristics of ocular surface and orbit tumors in the Southeast of China and explore the method to differentiate the benign and malignant masses.Materials and methods3468 patients ...
Yuan Lin   +22 more
doaj   +1 more source

The ocular surface in keratoconjunctivitis sicca [PDF]

open access: yesEye, 1989
The ocular surface is altered in kerato-conjunctivitis sicca, a disorder of aqueous tear production. Many of the factors leading to these surface changes are now more clearly understood and are discussed in this paper.
A J, Bron, L S, Mengher
openaire   +2 more sources

Impression cytology of the ocular surface [PDF]

open access: yesBritish Journal of Ophthalmology, 2005
Impression cytology refers to the application of a cellulose acetate filter to the ocular surface to remove the superficial layers of the ocular surface epithelium. These cells can then be subjected to histological, immunohistological, or molecular analysis. Proper technique is essential as the number of cells sampled can vary considerably.
R, Singh   +4 more
openaire   +2 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei   +17 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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