Results 21 to 30 of about 8,353,130 (346)

Immune regulation of the ocular surface

Experimental Eye Research, 2022
Despite constant exposure to various environmental stimuli, the ocular surface remains intact and uninflamed while maintaining the transparency of the cornea and its visual function. This 'immune privilege' of the ocular surface is not simply a result of the physical barrier function of the mucosal lining but, more importantly, is actively maintained ...
Yihe Chen, Shudan Wang, Hamid Alemi, Thomas Dohlman, Reza Dana   +4 more
openaire   +3 more sources

Dynamics of ocular surface topography [PDF]

Eye, 2006
To investigate fluctuations in the ocular surface, we used high-speed videokeratoscopy (50 Hz) to measure the dynamics of the ocular surface topography.Ocular surface height difference maps were computed to illustrate the changes in the tear film in the inter-blink interval.
Zhu, Mingxia, Collins, Michael, Iskander, Daoud   +2 more
openaire   +4 more sources

Current Evidence on the Ocular Surface Microbiota and Related Diseases

Microorganisms, 2020
The ocular surface microbiota refers to the resident non-pathogenic microorganisms that colonize conjunctiva and cornea. Several studies have shown that ocular surface epithelial cells can respond selectively to specific components of ocular pathogenic ...
Francesco Petrillo, Danilo Pignataro, Maria Annunziata Lavano   +2 more
exaly   +2 more sources

Topical glaucoma medications - Clinical implications for the ocular surface. [PDF]

The ocular surface, 2022
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility of the compound.
F. Fineide, N. Lagali, M. Adil, R. Arita, M. Kolko, J. Vehof, T. Utheim   +6 more
semanticscholar   +2 more sources

Establishment of a nomogram model to predict malignant risk in patients with ocular surface squamous neoplasia and ocular surface squamous epithelial tumors [PDF]

Frontiers in Oncology
ObjectiveTo develop and internally validate a nomogram to predict the probability that a clinically suspected ocular surface squamous epithelial tumor is histopathologically malignant.MethodsThis retrospective study included 92 patients with ocular ...
Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +53 more
doaj   +2 more sources

Tribology and the Ocular Surface [PDF]

Clinical Ophthalmology, 2022
Tribology is known as the science of friction, lubrication and the determination of what occurs when two surfaces slide against one another. The required partners in this science are a minimum of two surfaces and relative motion. Tribology could be a key factor in dissecting the issues that surround and confound dry eye in patients as well as contact ...
Chris W Lievens, Elyse Rayborn
openaire   +3 more sources

TFOS lifestyle: Impact of the digital environment on the ocular surface.

The ocular surface, 2023
Eye strain when performing tasks reliant on a digital environment can cause discomfort, affecting productivity and quality of life. Digital eye strain (the preferred terminology) was defined as "the development or exacerbation of recurrent ocular ...
J. Wolffsohn, Gareth Lingham, L. Downie, B. Huntjens, Takenori Inomata, Saleel Jivraj, E. Kobia-Acquah, Alex Muntz, Karim Mohamed-Noriega, S. Plainis, Michael L. Read, Rony R. Sayegh, Sumeer Singh, T. Utheim, J. Craig   +14 more
semanticscholar   +1 more source

The cGAS-STING pathway-dependent sensing of mitochondrial DNA mediates ocular surface inflammation

Signal Transduction and Targeted Therapy, 2023
The innate immune response is the main pathophysiological process of ocular surface diseases exposed to multiple environmental stresses. The epithelium is central to the innate immune response, but whether and how innate immunity is initiated by ocular ...
Weijie Ouyang, Shoubi Wang, Dan Yan, Jieli Wu, Yunuo Zhang, Wei Li, Jiaoyue Hu, Zuguo Liu   +7 more
semanticscholar   +1 more source

Possible Strategies to Mitigate Placebo or Vehicle Response in Dry Eye Disease Trials: A Narrative Review

Ophthalmology and Therapy, 2023
Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs and symptoms. However, patients with DED have very limited treatment options for management of both signs and symptoms of ...
Michela Montecchi-Palmer, Min Wu, Maurizio Rolando, Charis Lau, Victor L. Perez Quinones, Reza Dana   +5 more
doaj   +1 more source

Safety and Efficacy of Corneal Cross-Linking in Patients Affected by Keratoconus: Long-Term Results

Medical Sciences, 2023
The present study evaluated the effectiveness and safety of corneal collagen cross-linking (CXL). A total of 886 eyes with progressive keratoconus were enrolled in a retrospective cohort study in a tertiary care university hospital.
Karl Anders Knutsson, Paola Noemi Genovese, Giorgio Paganoni, Oriella Ambrosio, Giulio Ferrari, Arianna Zennato, Michela Caccia, Madeleine Cataldo, Paolo Rama   +8 more
doaj   +1 more source