Results 21 to 30 of about 1,855 (148)

Xeroderma Pigmentosum [PDF]

, 2011
Xeroderma pigmentosum (XP) is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers.
Lehmann, Alan R, McGibbon, David, Stefanini, Miria   +2 more
core   +3 more sources

Desmoplastic melanoma: a challenge for the oncologist [PDF]

, 2017
To evaluate clinical, pathologic and genetic features of desmoplastic melanoma (DM).MATERIALS & METHODS: Analysis of all DM records from 1991 to 2015.
LOSI, Lorena, Maccaferri, Monia, MANFREDINI, Marco, PELLACANI, Giovanni, PONTI, Giovanni, TOMASI, Aldo   +5 more
core   +1 more source

Update on Immune Checkpoint Inhibitors for Conjunctival Melanoma [PDF]

, 2022
The management of conjunctival melanoma is challenging due to the more frequent local recurrence and metastasis compared to other conjunctival neoplasms.
Daniel, Claire, Esmaeli, Bita, Sa, Ho-Seok   +2 more
core   +3 more sources

Hemangiosarcoma of the third eyelid in a horse [PDF]

, 2009
A 12-year-old Belgian Warmblood mare was referred to the equine clinic of the Faculty of Veterinary Medicine (Ghent University) for a mass on the third eyelid of the right eye. The horse had been having a recurrent red-tinged ocular discharge for several
Chiers, Koen, Ducatelle, Richard, Gasthuys, Frank, Vandecasteele, Maximilien, Wegge, Beatrice   +4 more
core  

A phase II study of dacetuzumab (SGN-40) in patients with relapsed diffuse large B-cell lymphoma (DLBCL) and correlative analyses of patient-specific factors [PDF]

, 2014
BACKGROUND: Patients with DLBCL who are ineligible for or have relapsed after aggressive salvage chemotherapy have a poor prognosis. CD40 is expressed on multiple B-cell neoplasms including DLBCL and is a potential target for immunotherapy.
Advani, Ranjana, Ansell, Stephen M, Bartlett, Nancy L, Cheson, Bruce D, de Vos, Sven, Drachman, Jonathan G, Forero-Torres, Andres, Furman, Richard R, Kahl, Brad, Kaplan, Henry, Timmerman, John, Whiting, Nancy C, Winter, Jane N   +12 more
core   +2 more sources

Genome-wide RNA-Sequencing analysis reveals a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery [PDF]

, 2017
Fibrosis-related events play a part in most blinding diseases worldwide. However, little is known about the mechanisms driving this complex multifactorial disease.
A Dobin, A Joannes, A Mahale, A Mortazavi, A Sokolović, AC Lake, AJ Haak, B Eyden, B Hinz, B Hinz, BA Mast, BL Riser, C Esnault, C Yu-Wai-Man, C Yu-Wai-Man, CA Fielding, D Bergamaschi, D Broadway, DW Esson, EM Addicks, EN Olson, G Bindea, H Guo, H Li, H Li, H Tao, HP Lorenz, HR Mason, IH Oh, J Ji, J Wang, J Yang, JC Bleacher, JJ Brown, JM Matthews, JS Stumhofer, K Akino, K Alitalo, K Seki, KA Frewer, KL Du, KW Liechty, L Li, M Aoyama, M Sabbah, MI Love, MP Popp, MR Namazi, N Erez, P Shannon, PG Pelicci, PO Yoon, R Gaujoux, S Anders, S Banerjee, S Kim, T Imai, T Luedde, T Minami, T Nakamura, TA Wynn, TH Sisson, TT Le, X Zhang, Y Benjamini, Y Drabsch, Y Su, Z Wang, Z Wang   +68 more
core   +2 more sources

Mammalian Tolerance to Amino Acid Heterochirality

ChemBioChem, Accepted Article.
Organisms use amino acids predominantly in l‐configuration. On the other hand, a series of studies show that a variety of d‐amino acids also occur in mammals and amino acid homochirality is not complete. Mammals de novo synthesize most amino acids with l‐configuration, but serine and aspartate are converted from l‐ to d‐configuration by endogenous ...
Jumpei Sasabe, Sakiko Taniguchi, Kenichiro Adachi, Xuan Tran, Masataka Suzuki   +4 more
wiley   +1 more source

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. [PDF]

, 2009
BRAF and NRAS are common targets for somatic mutations in benign and malignant neoplasms that arise from melanocytes situated in epithelial structures, and lead to constitutive activation of the mitogen-activated protein (MAP) kinase pathway.
Barsh, Gregory S, Bastian, Boris C, Bauer, Jürgen, Bezrookove, Vladimir, Gaugler, Lona, Green, Gary, O'Brien, Joan M, Simpson, Elizabeth M, Van Raamsdonk, Catherine D   +8 more
core  

Intraoperative High-Dose Rate of Radioactive Phosphorus 32 Brachytherapy for Diffuse Recalcitrant Conjunctival Neoplasms [PDF]

JAMA Ophthalmology, 2015
Adjunct treatments for conjunctival malignancies are needed when standard therapy provides limited benefits or fails.To describe the results of patients with diffuse conjunctival neoplasms treated with radioactive phosphorus 32 (32P)-impregnated flexible film.This retrospective case series between January 1, 2010, and January 1, 2013, was conducted at ...
Gil'ad N. Cohen, Beryl McCormick, Christopher A. Barker, David H. Abramson, David H. Abramson, Brian P. Marr, Brian P. Marr, Matthew J. Williamson   +7 more
openaire   +3 more sources

A one‐year efficacy assessment of subcutaneous immunotherapy in dust mite allergic rhinitis patients based on clinical symptoms and objective biomarkers

Eye &ENT Research, EarlyView.
Abstract Objective To evaluate the 1‐year efficacy of subcutaneous immunotherapy (SCIT) in treating dust mite‐induced allergic rhinitis (AR) and establish objective biomarkers for efficacy monitoring. Methods Fifty‐nine AR patients underwent 1‐year SCIT. Subjective symptoms were assessed via total nasal symptom score (TNSS), combined symptom/medication
Jingwen Wang, Xu Xu, Xu Zhang, Yuan Zhang, Jingyun Li   +4 more
wiley   +1 more source