Results 51 to 60 of about 16,148 (213)

Alterações oculares e imunohistoquímicas na conjuntiva e glândula lacrimal de pacientes submetidos ao transplante de medula óssea [PDF]

, 2003
PURPOSE: The primary ocular targets of chronic graft-versus-host disease (GVHD) are the lacrimal gland (LG) and the conjunctiva, and their involvement results in keratoconjunctivitis sicca (KCS).
Campos, Mauro Silveira de Queiroz, Cunha, Rosana Nogueira Pires da, Dulley, Frederico Luis, Foster, Charles Stephen, Rojas, Bianca   +4 more
core   +2 more sources

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

A 17-year-old male with a Small Bowel Neuroendocrine Tumor: flushing differential diagnosis

World Allergy Organization Journal, 2017
Background Neuroendocrine tumors (NETs) are heterogeneous neoplasms that originate from cells with a secretory function. Small bowel NETs (SB-NETs) are related to serotonin hypersecretion which causes: flushing, diarrhea, abdominal pain ...
Maria Alejandra Forero Molina, Elizabeth Garcia, Deyanira Gonzalez-Devia, Rafael García-Duperly, Alonso Vera   +4 more
doaj   +3 more sources

Ocular surface squamous neoplasia in Malaysia: A 5-year review

Taiwan Journal of Ophthalmology
PURPOSE: The purpose of the study was to review the demographic profile, risk factors, clinical presentations, and treatment outcomes in patients with ocular surface squamous neoplasia (OSSN) at government cornea centers in Malaysia.
Nor Sharina Binti Yusof, Ahmad Anwaar Muhammad Saifullah, Che Mahiran Che Daud, Rosilah Mohamad, Rohanah Alias   +4 more
doaj   +1 more source

Ocular pathology of uncommon hematologic malignancies: a case series

Journal of Medical Case Reports, 2007
Introduction In general, ocular complications of hematologic malignancies such as leukemia are well documented. However, reports of ocular involvement in such diseases as lymphomatoid granulomatosis and chronic myelomonocytic leukemia are uncommon.
Head James E, Shen Defen, Santiago-Maysonet Maribel, Bishop Rachel J, Chan Chi-Chao   +4 more
doaj   +1 more source

p16INK4A expression is frequently increased in periorbital and ocular squamous lesions [PDF]

, 2015
Backgroundp16 expression is a well established biomarker of cervical dysplasia and carcinoma arising from high risk human papilloma virus infection. Increased p16 expression is also seen in squamous neoplasms arising at other sites, including head, neck,
Bobby S. Korn, Bradford W. Lee, Don O. Kikkawa, Jean-Paul Abboud, Jonathan H. Lin, Karra Jones, Peter J. Kobalka, Xiaoyan Liao   +7 more
core   +2 more sources

Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore, Emma Ryan, Annabel Stevenson   +2 more
wiley   +1 more source

Severe Case of Peripheral Leukocytosis Initially Diagnosed as Myelodysplastic Syndrome/Myeloproliferative Neoplasm, Unclassifiable, but Possibly Prefibrotic Primary Myelofibrosis [PDF]

, 2014
Leukocytosis is occasionally seen in patients with presumptive but undiagnosed myeloproliferative disorders (MPD). A 74-year-old woman was admitted to our hospital for tarry stools, anemia, and marked peripheral leukocytosis of 1.4×105/μL ...
Hiramatsu, Yasushi, Kasahara, Akinori, Kondo, Eisei, Matsumura, Tadashi, Noguchi, Toshio, Ota, Seisuke, Takada, Saimon, Tanimoto, Mitsune, Umena, Sachio   +8 more
core   +1 more source

Bilateral Conjunctival Lesions in Blastic Plasmacytoid Dendritic Cell Neoplasm

Journal of Clinical and Experimental Hematopathology, 2011
The purpose of this study is to report on a patient who developed conjunctival lesions of blastic plasmacytoid dendritic cell neoplasm (BPDCN) after radiation to skin lesions of the same pathological type. A 79-year-old man developed salmon-pink lesions in the lower fornix of the conjunctiva of both eyes and biopsy revealed BPDCN.
Toshihiko, Matsuo, Kouichi, Ichimura, Takehiro, Tanaka, Shin, Morizane, Keiji, Iwatsuki, Motoharu, Eguchi, Tadashi, Yoshino   +6 more
openaire   +3 more sources

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source