Results 51 to 60 of about 494,310 (275)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Solving the B-SAT Problem Using Quantum Computing: Smaller Is Sometimes Better

Entropy
This paper aims to outline the effectiveness of modern universal gate quantum computers when utilizing different configurations to solve the B-SAT (Boolean satisfiability) problem.
Ahmad Bennakhi, Gregory T. Byrd, Paul Franzon   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Study of elastic system fibers in human gingiva [PDF]

RGO: Revista Gaúcha de Odontologia
Objective: To map the participation of the elastic system fibers of human gingiva. Methods: To conduct this study, fragments of human gingiva from ten individuals aged between 18 and 60 years, removed after periodontal surgery for prosthetic purposes ...
Walter Augusto Soares Machado, Eduardo Muniz Barreto Tinoco, Renata Castanheira Machado, Gerson Cotta-Pereira   +3 more
doaj  

Guaranteeing no interaction between functional dependencies and tree-like inclusion dependencies

, 2001
Functional dependencies (FDs) and inclusion dependencies (INDs) are the most fundamental integrity constraints that arise in practice in relational databases.
Mark Levene, Levene, Mark, George Loizou, Loizou, George   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

MULTIPLE FOLDING OF REGULAR STRUCTURES VIA SOLVING LOGIC EQUATIONS

Informatika, 2016
The problem under consideration is to reduce the area of the layout of regular VLSI structures by means of their multiple folding. The method of solving the key problem of multiple folding, which is implementability checking of the folding set, is ...
L. D. Cheremisinova
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Biocomputing system of living cells [PDF]

Computer Science Journal of Moldova, 2002
The aim of this paper1 is to show that the process of gene transcription can be represented as a finite automaton illustrating the processing of input/output signals in living cells at DNA level.
Aurelia Profir
doaj