Results 91 to 100 of about 15,738 (210)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Understanding About Pesticide Handling Practice and Acute Pesticide Poisoning Among Farmers in Bangladesh

Public Health Challenges, Volume 5, Issue 2, June 2026.
Unsafe pesticide handling and limited awareness among Bangladeshi farmers lead to a high prevalence of acute pesticide poisoning and associated health problems. Strengthening training, awareness, and regulatory interventions is essential to promote safe pesticide practices and reduce occupational health risks.
Md. Mejbah Uddin Mithu, Sadia Akter Shormela, Abdullah Jaman, Md. Shahinul Islam, Mahfuza Mubarak   +4 more
wiley   +1 more source

Demographic distribution of allergic conjunctivitis in selected schools in Ovia North East Local Government Area, Benin City, Edo State

Ibom Medical Journal
Background: The burden of allergic diseases and conjunctivitis has been on the increase, especially in developing countries, prompting several studies across varying populations to investigate the causes and prevalence of these conditions ...
Okoro CC, Odigie OM, Ozigis M
doaj   +4 more sources

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Age‐dependent reductions in natural moisturizing factor and caspase‐14 in paediatric atopic dermatitis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Risa Fukuda, Kyongsun Pak, Hazuki Yasuda, Tomoko Kawai, Kenichiro Hata, Naoko Mochimaru, Marie Takenouchi, Ryo Tanaka, Rena Hashimoto, Yuhki Ueda, Susumu Hashimoto, Keisuke Shimazaki, Kazue Yoshida   +12 more
wiley   +1 more source

Efficacy and Safety of Anti‐IL‐4Rα Stapokibart in Elderly Patients With Moderate‐To‐Severe Atopic Dermatitis

International Journal of Dermatology, Volume 65, Issue 6, Page 1185-1194, June 2026.
ABSTRACT Background Elderly patients with moderate‐to‐severe atopic dermatitis (AD) often exhibit more heterogeneous inflammatory profiles compared with younger adults. To evaluate the efficacy and safety of stapokibart, an anti‐interleukin‐4 receptor α subunit (IL‐4Rα) monoclonal antibody, in different age subgroups.
Yan Zhao, Litao Zhang, Liming Wu, Bin Yang, Jinyan Wang, Yumei Li, Qingchun Diao, Jingyi Li, Qing Sun, Xiaohong Zhu, Xiaoyong Man, Lihua Wang, Yanyan Feng, Tao Cai, Huiming Zeng, Linfeng Li, Jianyun Lu, Hong Ren, Fuqiu Li, Qianjin Lu, Xiaohua Tao, Rong Xiao, Chao Ji, Jing Sun, Yanping Qiu, Bo Chen, Jianzhong Zhang   +26 more
wiley   +1 more source

Viral Conjunctivitis Rates Unchanged Before and During the COVID-19 Pandemic in an Ophthalmology Clinic

Clinical Ophthalmology
Amber N Piazza,1 Peter A Downie,1,2 Michael S Lee,3 Bruce R Lindgren,4 Joshua H Olson3 1Medical School, University of Minnesota, Minneapolis, MN, 55455, USA; 2Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI ...
Piazza AN, Downie PA, Lee MS, Lindgren BR, Olson JH   +4 more
doaj  

Long-term effects of air pollution on daily outpatient visits for allergic conjunctivitis from 2013 to 2020: a time-series study in Urumqi, China

Frontiers in Public Health
IntroductionThis study aimed to elucidate the effects of outdoor air pollution and allergic conjunctivitis and population-based lagged effects of air pollution.MethodsWe included data on six major air pollutants, PM10, PM2.5, carbon monoxide (CO), sulfur
Dongwei Liu, Siyu Gui, Xinchen Wang, Qianqian Wang, Jianchao Qiao, Fangbiao Tao, Liming Tao, Zhengxuan Jiang, Xianglong Yi   +8 more
doaj   +1 more source

Fruquintinib Plus TAS‐102 With or Without SBRT as Third‐ Or Later‐Line Therapy for Metastatic Colorectal Cancer: Preliminary Results From a Prospective Phase II Trial

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Both fruquintinib and TAS‐102 monotherapies are guideline‐recommended for third‐line treatment of metastatic colorectal cancer (mCRC). This study aimed to analyze the preliminary outcomes of fruquintinib combined with TAS‐102, with or without stereotactic body radiation therapy (SBRT), as a third‐ or later‐line therapy for mCRC.
Yi Wang, Jianfen Xu, Linchun Liang, Yunjie Chen, Leizheng Fei, Jing Hu, Jianjiong Li, Yi Lu, Feng Ren, Ke Chen, Yanping Shen, Qingsong Tao, Zhi Fang, Kaitai Liu, Hua Ye, Jing Zhang, Yunbao Xu, Haoxun Mao, Chen Zhang, Chuangzhou Rao   +19 more
wiley   +1 more source

Updates in the treatment of ocular allergies

Journal of Asthma and Allergy, 2010
Osmo Kari1, K Matti Saari21Department of Allergology, Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland; 2Department of Ophthalmology, University of Turku, Turku, FinlandAbstract: Allergic diseases have greatly increased ...
Osmo Kari, K Matti Saari
doaj