Results 1 to 10 of about 148,201 (169)
The lectin ArtinM induces recruitment of rat mast cells from the bone marrow to the peritoneal cavity. [PDF]
PLoS ONE, 2010 BACKGROUND: The D-mannose binding lectin ArtinM is known to recruit neutrophils, to degranulate mast cells and may have potential therapeutic applications. However, the effect of ArtinM on mast cell recruitment has not been investigated.
Patricia Andressa de Almeida Buranello +5 more
doaj +1 more source
IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases?
Antibodies, 2020 Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive.
Christophe Pellefigues
doaj +1 more source
Semaphorin-3 Promotes Specific Immunotherapy Effects on Experimental Food Allergy
Journal of Immunology Research, 2022 Sustaining higher frequency of mast cells in the allergic lesion site has been recognized. Factors causing high numbers of mast cells in the local tissues are not fully understood yet.
Huang Huang +11 more
doaj +1 more source
Current Gastroenterology Reports, 2010 Mast cells have been considered for many years to participate specifically in allergic reactions through the release of cytokines, chemokines, proteases, leukotrienes, and bioactive polyamines. Emerging roles for mast cells have been identified recently, which highlight their relevance in both innate and adaptive immunity.
Terez, Shea-Donohue +3 more
openaire +2 more sources
Regulation of osteoclastogenesis by mast cell in rheumatoid arthritis
Arthritis Research & Therapy, 2021 Background In the pathogenesis of rheumatoid arthritis (RA), the role of mast cells has not been revealed clearly. We aimed to define the inflammatory and tissue-destructive roles of mast cells in rheumatoid arthritis (RA).
Kyoung-Woon Kim +6 more
doaj +1 more source
Mast Cells: A New Frontier for Cancer Immunotherapy
Cells, 2021 Mast cells are unique tissue-resident immune cells of the myeloid lineage that have long been implicated in the pathogenesis of allergic and autoimmune disorders. More recently, mast cells have been recognized as key orchestrators of anti-tumor immunity,
Jake N. Lichterman, Sangeetha M. Reddy
doaj +1 more source
Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells
Cells, 2022 Mast cells are tissue-resident cells that contribute to allergic diseases, among others, due to excessive or inappropriate cellular activation and degranulation. Therapeutic approaches to modulate mast cell activation are urgently needed.
Piper A. Robida +15 more
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The mast cell and mast cell disease
Journal of the American Academy of Dermatology, 1995 Mast cell disease or mastocytosis is a heterogeneous group of clinical disorders characterized by the proliferation and accumulation of mast cells in a variety of tissues, most often the skin. The signs and symptoms of mast cell disease are varied, dependent on the localization of mast cells in different organs and the local and systemic effects of ...
J, Longley, T P, Duffy, S, Kohn
openaire +2 more sources
Degranulated mast cells and TNF-α in oral lichen planus and oral lichenoid reactions diseases
Advanced Biomedical Research, 2012 Background: The objective of this study was to assess mast cells and TNF-α in oral lichen planus (OLP) and oral lichenoid reactions (OLR) patients as diagnostic marker to the differential diagnosis of OLP and OLR diseases.
Parichehr Ghalayani +2 more
doaj +1 more source