Results 11 to 20 of about 147,604 (268)
IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases?
Antibodies, 2020 Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive.
Christophe Pellefigues
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Semaphorin-3 Promotes Specific Immunotherapy Effects on Experimental Food Allergy
Journal of Immunology Research, 2022 Sustaining higher frequency of mast cells in the allergic lesion site has been recognized. Factors causing high numbers of mast cells in the local tissues are not fully understood yet.
Huang Huang +11 more
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Current Gastroenterology Reports, 2010 Mast cells have been considered for many years to participate specifically in allergic reactions through the release of cytokines, chemokines, proteases, leukotrienes, and bioactive polyamines. Emerging roles for mast cells have been identified recently, which highlight their relevance in both innate and adaptive immunity.
Terez, Shea-Donohue +3 more
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Regulation of osteoclastogenesis by mast cell in rheumatoid arthritis
Arthritis Research & Therapy, 2021 Background In the pathogenesis of rheumatoid arthritis (RA), the role of mast cells has not been revealed clearly. We aimed to define the inflammatory and tissue-destructive roles of mast cells in rheumatoid arthritis (RA).
Kyoung-Woon Kim +6 more
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Mast cell-mediated immune regulation in health and disease
Frontiers in Medicine, 2023 Mast cells are important components of the immune system, and they perform pro-inflammatory as well as anti-inflammatory roles in the complex process of immune regulation in health and disease.
Kottarappat N. Dileepan +8 more
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The mast cell and mast cell disease
Journal of the American Academy of Dermatology, 1995 Mast cell disease or mastocytosis is a heterogeneous group of clinical disorders characterized by the proliferation and accumulation of mast cells in a variety of tissues, most often the skin. The signs and symptoms of mast cell disease are varied, dependent on the localization of mast cells in different organs and the local and systemic effects of ...
J, Longley, T P, Duffy, S, Kohn
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Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells
Stem Cell Reports, 2018 Summary: Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently, drug discovery is
Mari-Liis Kauts +13 more
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Brazilian Journal of Medical and Biological Research, 2023 As an important component of solid tumors, mast cells show specific phenotypes in various tumor microenvironments. However, the precise mechanism of mast cell accumulation and the phenotypic features of thyroid cancer (TC) remain largely unknown.
Yanli Hou +5 more
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Degranulated mast cells and TNF-α in oral lichen planus and oral lichenoid reactions diseases
Advanced Biomedical Research, 2012 Background: The objective of this study was to assess mast cells and TNF-α in oral lichen planus (OLP) and oral lichenoid reactions (OLR) patients as diagnostic marker to the differential diagnosis of OLP and OLR diseases.
Parichehr Ghalayani +2 more
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