Results 21 to 30 of about 4,610,022 (310)
Degranulated mast cells and TNF-α in oral lichen planus and oral lichenoid reactions diseases
Advanced Biomedical Research, 2012 Background: The objective of this study was to assess mast cells and TNF-α in oral lichen planus (OLP) and oral lichenoid reactions (OLR) patients as diagnostic marker to the differential diagnosis of OLP and OLR diseases.
Parichehr Ghalayani +2 more
doaj +1 more source
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells
Stem Cell Reports, 2018 Summary: Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently, drug discovery is
Mari-Liis Kauts +13 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2023 As an important component of solid tumors, mast cells show specific phenotypes in various tumor microenvironments. However, the precise mechanism of mast cell accumulation and the phenotypic features of thyroid cancer (TC) remain largely unknown.
Yanli Hou +5 more
doaj +1 more source
Harnessing the Power of Mast Cells in unconventional Immunotherapy Strategies and Vaccine Adjuvants
Cells, 2020 Mast cells are long-lived, granular, myeloid-derived leukocytes that have significant protective and repair functions in tissues. Mast cells sense disruptions in the local microenvironment and are first responders to physical, chemical and biological ...
Steven Willows, Marianna Kulka
doaj +1 more source
Cell Communication and Signaling, 2018 Background Mast cells may activate fibroblasts and contribute to remodeling processes in the lung. However, the mechanism behind these actions needs to be further investigated. Fibroblasts are major regulators of on-going remodeling processes.
Mariam Bagher +5 more
doaj +1 more source
Local Mast Cell Activation Promotes Neovascularization
Cells, 2020 Mast cells have been associated with arteriogenesis and collateral formation. In advanced human atherosclerotic plaques, mast cells have been shown to colocalize with plaque neovessels, and mast cells have also been associated with tumor vascularization.
Ilze Bot +6 more
doaj +1 more source
Toxins, 2016 The association of colitis with colorectal cancer has become increasingly clear with mast cells being identified as important inflammatory cells in the process.
Shan Wang +7 more
doaj +1 more source
Mast Cells and Skin and Breast Cancers: A Complicated and Microenvironment-Dependent Role
Cells, 2021 Mast cells are important sentinel cells in host defense against infection and major effector cells in allergic disease. The role of these cells in cancer settings has been widely debated.
Mark R. Hanes +2 more
doaj +1 more source
, 2008 Activated mast cells are a major source of the eicosanoids PGD(2) and leukotriene C(4) (LTC(4)), which contribute to allergic responses. These eicosanoids are produced following the ERK1/2-dependent activation of cytosolic phospholipase A(2), thus ...
Hye Sun Kuehn +11 more
core +2 more sources