Results 21 to 30 of about 294,471 (310)
British Journal of Haematology, 2005 In May 2003, a 65-year-old white male presented with weight loss, night sweats, pruritus, diarrhoea, and joint pain. Radiographic studies showed hepatosplenomegaly, abdominal lymphadenopathy and both osteoblastic and osteolytic bone lesions. Bone marrow biopsy showed extensive mast cell infiltration and effacement of marrow structure with reduction of ...
Olaf, Penack +2 more
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JCI Insight, 2021 Ozone is a highly reactive environmental pollutant with well-recognized adverse effects on lung health. Bronchial hyperresponsiveness (BHR) is one consequence of ozone exposure, particularly for individuals with underlying lung disease.
Xiaomei Kong +18 more
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Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells
Cells, 2022 Mast cells are tissue-resident cells that contribute to allergic diseases, among others, due to excessive or inappropriate cellular activation and degranulation. Therapeutic approaches to modulate mast cell activation are urgently needed.
Piper A. Robida +15 more
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Isolation and Culture of Peritoneal Cell-derived Mast Cells
Bio-Protocol, 2014 The generation of mast cells for in vitro studies comes from a variety of sources including mast cell lines (MC/9) (McCurdy et al., 2001), bone marrow-derived mast cells (BMMCs) (Supajatura et al., 2001), skin-derived mast cells (FSMCs) (Matsushima et al.
Krisztina Vukman +3 more
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Toxins, 2016 The association of colitis with colorectal cancer has become increasingly clear with mast cells being identified as important inflammatory cells in the process.
Shan Wang +7 more
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Future Needs in Mast Cell Biology. [PDF]
, 2019 The pathophysiological roles of mast cells are still not fully understood, over 140 years since their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct "subpopulations" of mast cells based on a relatively small ...
de Paulis, Amato +3 more
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Isolation and Culture of Bone Marrow-derived Mast Cells
Bio-Protocol, 2014 The generation of mast cells for in vitro studies comes from a variety of sources including mast cell lines (MC/9) (McCurdy et al., 2001), bone marrow-derived mast cells (BMMCs) (Supajatura et al., 2001), skin-derived mast cells (FSMCs) (Matsushima et al.
Krisztina Vukman +3 more
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Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]
, 2010 Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
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Journal for ImmunoTherapy of Cancer, 2019 Background Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the nature, regulation, function, and clinical relevance of mast cells in human gastric cancer (GC) are ...
Yipin Lv +18 more
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The mast cell and mast cell disease
Journal of the American Academy of Dermatology, 1995 Mast cell disease or mastocytosis is a heterogeneous group of clinical disorders characterized by the proliferation and accumulation of mast cells in a variety of tissues, most often the skin. The signs and symptoms of mast cell disease are varied, dependent on the localization of mast cells in different organs and the local and systemic effects of ...
J, Longley, T P, Duffy, S, Kohn
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