Results 31 to 40 of about 147,604 (268)
Journal for ImmunoTherapy of Cancer, 2019 Background Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the nature, regulation, function, and clinical relevance of mast cells in human gastric cancer (GC) are ...
Yipin Lv +18 more
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Mast Cells and Neuroinflammation [PDF]
Medical Science Monitor Basic Research, 2014 It has been determined that there is extensive communication between the immune system and the central nervous system (CNS). Proinflammatory cytokines play a key role in this communication. There is an emerging realization that glia and microglia, in particular, (which are the brain's resident macrophages), are an important source of inflammatory ...
Dong, Hongquan +2 more
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Perivascular mast cells regulate vein graft neointimal formation and remodeling [PDF]
PeerJ, 2015 Objective. Emerging evidence suggests an important role for mast cells in vein graft failure. This study addressed the hypothesis that perivascular mast cells regulate in situ vascular inflammatory and proliferative responses and subsequent vein graft ...
Junxi Wu +9 more
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Mast Cells and Skin and Breast Cancers: A Complicated and Microenvironment-Dependent Role
Cells, 2021 Mast cells are important sentinel cells in host defense against infection and major effector cells in allergic disease. The role of these cells in cancer settings has been widely debated.
Mark R. Hanes +2 more
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BMC Immunology, 2010 Background Mast cells have recently gained new importance as immunoregulatory cells that are involved in numerous pathological processes. One result of these processes is an increase in mast cell numbers at peripheral sites.
Pastor Maria +8 more
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Relationship between numerous mast cells and early follicular development in neonatal MRL/MpJ mouse ovaries. [PDF]
PLoS ONE, 2013 In the neonatal mouse ovary, clusters of oocytes called nests break into smaller cysts and subsequently form individual follicles. During this period, we found numerous mast cells in the ovary of MRL/MpJ mice and investigated their appearance and ...
Teppei Nakamura +6 more
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Analysis of human lung mast cells by single cell RNA sequencing
Frontiers in Immunology, 2023 Mast cells are tissue-resident cells playing major roles in homeostasis and disease conditions. Lung mast cells are particularly important in airway inflammatory diseases such as asthma.
Elin Rönnberg +15 more
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Frontiers in Oncology, 2021 Tumor cells require signaling and close interaction with their microenvironment for their survival and proliferation. In the recent years, Mast cells have earned a greater importance for their presence and role in cancers. It is known that mast cells are
Deeksha Mehtani, Niti Puri
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Histamine and TNF-α release by rat peritoneal mast cells stimulated with Trichomonas vaginalis
Parasite, 2011 Mast cells have been reported to be predominant in the vaginal smears of patients infected with T. vaginalis. In this study, we investigated whether T. vaginalis could induce mast cells to migrate and to produce TNF-α and histamine.
Im S.J. +6 more
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Mast cells and canine mast cell tumours. A review [PDF]
Veterinary Quarterly, 2004 This article reviews the literature on mast cells and tumours derived from mast cells in the dog. Mast cells play a central role in inflammatory and immune reactions. Mast cells, normal and neoplastic, contain and release important biologically active substances: heparin, histamine, eosinophilic chemotactic factor and proteolytic enzymes.
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