Results 51 to 60 of about 15,738 (210)

Correlation of tear film-specific immunoglobulin E assay with the skin prick test in allergic conjunctivitis

Delta Journal of Ophthalmology, 2017
Purpose The aim of this study was to investigate the correlation and validity of tear film allergen-specific immunoglobulin E (IgE) in relation to the skin prick test in diagnosing different types of allergic conjunctivitis. Design The study design was a
Basem M Ibrahim, Randa S Abdel-Latif
doaj   +1 more source

Dupilumab's Real‐World Efficacy and Safety Across Age Groups for Children and Adolescents With Paediatric Atopic Dermatitis

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Dupilumab is an anti‐interleukin (IL)‐4 receptor (IL‐4Rα) monoclonal antibody used to manage atopic dermatitis (AD). There is a paucity of real‐world Australian data for dupilumab in paediatric AD, especially regarding differences in clinical profiles between age groups.
Paul Sun Woo Kim, Jacqueline Tu, Kelvin Truong, Gloria Fong, William Luu, Peter Barclay, Melanie Wong, Li‐Chuen Wong   +7 more
wiley   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Clinical characteristics of allergic conjunctivitis in the Southern region of Saudi Arabia: a cross-sectional study

Therapeutic Advances in Ophthalmology
Background: Allergic conjunctivitis is a prevalent ocular condition characterized by inflammation of the conjunctiva due to hypersensitivity reactions to various allergens.
Waleed ALDhabaan, Saleh Ghulaysi, Albatool Alqahtani, Eman Hurissi, Manar M. Alamri, Almuhannad G. Alnami, Ahmed H. Sumayli, Yahya A. Dhamri, Amani A. Mosleh, Ethar A. Khawaji, Abdullah A. Alshahrani, Abdulsalam S. Alfaifi, Saja M. Alghamdi   +12 more
doaj   +1 more source

Spatial and temporal trends of conjunctivitis in Uganda, 2020–2023: A nationwide surveillance analysis

Journal of Interventional Epidemiology and Public Health
Introduction: Conjunctivitis is a common ocular condition with multiple infectious and non-infectious causes and remains an important public health concern in low-resource settings.
Gertrude Abbo, Richard Migisha, Benon Kwesiga, Patricia Eyu, Hilda Tendo Nansikombi, Lilian Bulage, Alex Riolexus Ario   +6 more
doaj   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

A One‐Strength Dose Escalation Regimen for Birch Pollen SCIT Is Safe and Tolerable in Children, Adolescents, and Adults

Allergy, EarlyView.
This study evaluated safety and tolerability of birch pollen SCIT during dose escalation with a new One‐Strength regimen (3 injections, Strength B) compared to the Standard regimen (7 injections, Strengths A and B) in patients aged 5–65 years. Safety and tolerability were comparable between the two regimens in adults, adolescents, and adolescents, as ...
Marek Jutel, Ludger Klimek, Michael Gerstlauer, Dana Troyke, Kristina Duwensee, Christian Vogelberg   +5 more
wiley   +1 more source

IgE Sensitization to Inhalant Allergens and Its Association with Allergic Diseases in Adults

Iranian Journal of Allergy, Asthma and Immunology, 2018
Allergic sensitization to inhalant allergens could be considered as a predictor in allergic diseases. The objective of this study was to assess IgE-mediated sensitization to inhalant allergens in allergic and non-allergic adults as well as the evaluation
Raheleh Shokouhi Shoormasti, Mohammad Reza Fazlollahi, Anoshirvan Kazemnejad, Behnoosh Tayebi, Fatemeh Nadali, Maryam Sharif Shoushtari, Shamim Khandan Alamdari, Majid Moslemi, Masoud Movehdi, Adriano Mari, Zahra Pourpak, Mostafa Moin   +11 more
doaj  

Patient‐Perceived Benefits of Named‐Patient Product Sublingual Immunotherapy in Allergic Rhinitis and Asthma: Primary Results From the ERAPP Real‐World Cohort Study

Allergy, EarlyView.
Evaluation en vie Réelle de l'Allergo‐Prescription en Pratique (ERAPP) is a large, prospective, real‐world cohort of children and adults initiating named‐patient product sublingual immunotherapy (NPP‐SLIT) in France. More than 80% of patients reported a clinically meaningful, expectation‐anchored benefit (Patient Benefit Index ≥ 1) at 12–15 months. The
Davide Caimmi, Abdelilah Abouelfath, Régis Lassalle, Séverine Lignot‐Maleyran, Emmanuelle Bignon, Patrick Blin, Evangéline Clark, Julien Cottet, Laure Carcaillon‐Bentata, Pascal Demoly   +9 more
wiley   +1 more source

The Early Efficacy of Topical Levocabastine in Patients with Allergic Conjunctivitis

Allergology International, 2006
Background: We investigated the early efficacy of topical levocabastine, an H1 histamine-receptor antagonist, in improving the clinical symptoms of allergic conjunctivitis. Methods: Thirty-six patients with allergic conjunctivitis were enrolled. One drop
Hiroshi Fujishima, Kazumi Fukagawa, Yoji Takano, Shigeki Okamoto, Yayoi Nakagawa, Eiichi Uchio, Norihiko Yokoi, Atsuki Fukushima, Etsuko Takamura   +8 more
doaj   +1 more source